Publications by authors named "Robert Labrom"

An accurate estimation of maximal voluntary muscle activation is critical for normalisation in scientific studies. Only a handful of studies appropriately normalise muscle activation data when investigating paraspinal muscle activity in populations such as adolescent idiopathic scoliosis (AIS). This neglect compromises the ability to interpret data.

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Purpose: Identification of adolescent idiopathic scoliosis (AIS) patients with mild curvatures who pose significant risk of progressing to severe levels of curvatures is of paramount importance for clinical care. This study aimed to compare segmental deformity changes in AIS sub-cohorts that are dichotomised by progression status.

Methods: Thirty-six female participants with Lenke 1 AIS curves were investigated with sequential MRIs during growth.

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Article Synopsis
  • The study aims to explore how axial plane deformity affects the worsening of spinal deformity in Adolescent Idiopathic Scoliosis (AIS) using sequential MRI scans of patients.
  • It involves 27 AIS patients, with observations showing that axial vertebral rotation (AVR) is highest at the curve's apex, which correlates positively with scoliosis severity and associated rib hump.
  • Findings suggest that while AVR increases during scoliosis progression, the most significant intravertebral rotation (IVR) occurs in the vertebrae around the apex, indicating these levels may play a crucial role in the condition's progression.
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Study Design: A prospective cohort study.

Objective: Detail typical three-dimensional segmental deformities and their rates of change that occur within developing adolescent idiopathic scoliosis (AIS) spines over multiple timepoints.

Summary Of Background Data: AIS is a potentially progressive deforming condition that occurs in three dimensions of the scoliotic spine during periods of growth.

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Purpose: Vertebral body tethering (VBT) is a recent procedure to correct and reduce spinal curves in skeletally immature patients with adolescent idiopathic scoliosis (AIS). The purpose of this systematic review and meta-analysis is to determine the expected curve reduction and potential complications for adolescent patients after VBT.

Methods: PubMed, Embase, Google Scholar and Cochrane databases were searched until February 2022.

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Adolescent Idiopathic Scoliosis (AIS) is a 3D spine deformity that also causes ribcage and torso distortion. While clinical metrics are important for monitoring disorder progression, patients are often most concerned about their cosmesis. The aim of this study was to automate the quantification of AIS cosmesis metrics, which can be measured reliably from patient-specific 3D surface scans (3DSS).

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Introduction: 3D Non-Contact surface scanning (3DSS) is used in both biomechanical and clinical studies to capture accurate 3D images of the human torso, and to better understand the shape and posture of the spine-both healthy and pathological. This study sought to determine the efficacy and accuracy of using 3DSS of the posterior torso, to determine the curvature of the spinal column in the lateral lying position.

Methods: A cohort of 50 healthy adults underwent 3DSS and Magnetic Resonance Imaging (MRI) to correlate the contours of the external spine surface with the internal spinal column.

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Study Design: Prospective cohort study.

Objectives: Investigate the progressive changes in pedicle morphometry and the spatial relationship between the pedicles and neurovascular structures in patients with AIS during growth. Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional spine deformity.

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Study Design: Cross-sectional study.

Objectives: To provide a comprehensive, multi-stage investigation of vertebral body (VB) and intervertebral disc (IVD) coronal plane deformities for adolescent idiopathic scoliosis (AIS) patients with a main thoracic curve type, using a series of sequential magnetic resonance images (MRIs). Despite numerous investigations of AIS deformity at the spinal segmental level, there is little consensus as to the major contributor to the lateral curvature of a scoliotic spine.

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Background: Adolescent idiopathic scoliosis is a common condition affecting 2.5% of the general population. Vertebral body stapling was introduced as a method of fusionless growth modulation for the correction of moderate idiopathic scoliosis (Cobb angles of 20-40°), and was claimed to be more effective than bracing and less invasive than fusion.

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Introduction: 3D non-contact surface scanners capture highly accurate, calibrated images of surface topography for 3D structures. This study sought to establish the efficacy and accuracy of using 3D surface scanning to characterise spinal curvature and sagittal plane contour.

Methods: 10 healthy female adults with a mean age of 25 years, (standard deviation: 3.

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Background: A new growing rod (GR) design, the semiconstrained growing rod (SCGR), with the added advantage of axial rotation freedom within the components, has been introduced at our center which has been shown to be growth friendly. We hypothesize that the SCGR system would reduce autofusion in vivo, thereby maximizing the coronal plane correction, T1-S1 growth, and the final correction achieved at definitive fusion for children with an early onset scoliosis.

Methods: In total, 28 patients had either single or dual 5.

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Objectives: Lemierre's syndrome cause by methicillin-sensitive is rare, but can lead to necrotizing pneumonia and septicaemia. When treating such patient with extracorporeal life support source control can be both challenging and controversial.

Methods: In this report we present a 12 year old male who presented with Lemierre's syndrome from which he developed septic shock and severe necrotizing pneumonia.

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Background: Axial vertebral rotation is a key characteristic of adolescent idiopathic scoliosis (AIS), and its reduction is one of the goals of corrective surgery. Recurrence of deformity after surgical correction may relate to rotation changes that occur in the anterior vertebral column after surgery, but whether any change occurs within the fused segment or in adjacent unfused levels following thoracoscopic anterior spinal fusion (TASF) is unknown. An analysis of measurements from an existing postoperative CT dataset was performed to investigate the occurrence of inter- and intra-vertebral rotation changes after TASF within and adjacent to the fused spinal segment and look for any relationships with the Cobb angle and rib hump in the two years after surgery.

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Study Design: Lung volumes and thoracic anatomy were measured from low-dose computed tomography (CT) scans preoperatively and 2 years following thoracoscopic anterior spinal fusion (TASF) for adolescent idiopathic scoliosis (AIS).

Objective: The aim of this study was to assess changes in lung volume after TASF surgical correction.

Summary Of Background Data: AIS patients are known to have decreased pulmonary function as a consequence of their spinal and ribcage deformity.

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Study Design: The aim of this study was to measure contributions of individual vertebra and disc wedging to coronal Cobb angle in the growing scoliotic spine using sequential magnetic resonance imaging (MRI). Clinically, the Cobb angle measures the overall curve in the coronal plane but does not measure individual vertebra and disc wedging. It was hypothesized that patients whose deformity progresses will have different patterns of coronal wedging in vertebrae and discs to those of patients whose deformities remain stable.

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Background Context: In recent years, there has been increasing appreciation of the need to treat scoliosis as a three-dimensional deformity.

Purpose: Assessment of surgical strategies and outcomes should consider not only the coronal plane correction but also derotation of the transverse plane deformity that can affect trunk appearance.

Study Design: This study included a cohort of 29 female adolescent idiopathic scoliosis patients who received thoracoscopic single rod anterior fusion (TASF) surgery.

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Objective: To investigate whether growing rod surgery for children with progressive idiopathic early onset scoliosis (EOS) effects activity and participation, and investigate factors that may affect this.

Study Design: Multicenter retrospective cohort study using prospectively collected data on 60 children with idiopathic EOS and significant scoliosis (defined as a Cobb angle >40°). Thirty underwent brace treatment, and 30, growth rod surgery.

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Study Design: Retrospective review of prospectively collected data.

Objectives: To analyze intervertebral (IV) fusion after thoracoscopic anterior spinal fusion (TASF) and explore the relationship between fusion scores and key clinical variables.

Summary Of Background Information: TASF provides comparable correction with some advantages over posterior approaches but reported mechanical complications, and their relationship to non-union and graft material is unclear.

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Purpose: The dimensions of the thoracic intervertebral foramen in adolescent idiopathic scoliosis (AIS) have not previously been quantified. Better understanding of the dimensions of the foramen may be useful in surgical planning. This study describes a reproducible method for measurement of the thoracic foramen in AIS using computed tomography (CT).

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Background: Adolescent idiopathic scoliosis is a complex three-dimensional deformity of the spine characterized by deformities in the sagittal, coronal, and axial planes. Spinal fusion using pedicle screw instrumentation is a widely used method for surgical correction in severe (coronal deformity, Cobb angle > 45°) adolescent idiopathic scoliosis curves. Understanding the anatomic difference in the pedicles of patients with adolescent idiopathic scoliosis is essential to reduce the risk of neurovascular or visceral injury through pedicle screw misplacement.

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Purpose: Cadaveric studies have previously documented a typical pattern of venous drainage within vertebral bodies (VBs), comprised primarily of the basivertebral vein. These studies, however, are limited by the number of samples available. MRI is able to provide 3D images of soft tissue structures in the spine, including the basivertebral vein without the use of contrast in both healthy controls and subjects with abnormal anatomy such as adolescent idiopathic scoliosis (AIS).

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Article Synopsis
  • - Adolescent Idiopathic Scoliosis (AIS) is a common spinal deformity influenced by asymmetrical gravitational forces, which may lead to increased deformity progression; the exact biomechanics aren't fully understood.
  • - A study used low-dose CT scans from 20 female scoliosis patients to evaluate torso segment masses and intervertebral joint moments, revealing that larger spinal curves (measured by Cobb angles) do not always correlate with higher joint moments.
  • - Findings indicate that the shape of the spinal curve affects joint moment distribution and suggest that significant corrective forces from braces or surgery are needed to combat the gravitational effects that contribute to scoliosis progression.
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Article Synopsis
  • - The study explores how two factors—repeated cyclic loading and freeze-thaw cycles—affect the stiffness of immature bovine thoracic spine motion segments, highlighting the need for consistency in biomechanical research methods.
  • - Results indicate that group tested with continuous cyclic loading saw significant reductions in stiffness for flexion/extension and lateral bending, while no major change was observed in axial rotation stiffness after 500 cycles.
  • - The findings suggest that comparisons between different in vitro studies can be valid up to 200 load cycles without significant changes in stiffness, which aids in planning future biomechanical research.
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