Economic Impact of Universal Hepatitis C Virus Testing for Middle-Aged Adults Who Inject Drugs.

Introduction: The objective of this study was to estimate the economic impact of providing universal hepatitis C virus testing in commercially insured middle-aged persons who inject drugs in the U.S.

Methods: This study developed a dynamic 10-year economic model to project the clinical and economic outcomes associated with hepatitis C virus testing among middle-aged adult persons who inject drugs, from a payer's perspective.

Cascade of Hepatitis C Virus Care Among Patients With Substance Use Disorders.

Introduction: Hepatitis C virus testing is recommended for people at high risk for infection, including those with substance use disorders. Little is known about the cascade of hepatitis C virus care (including testing, diagnosis, and treatments) among patients with substance use disorders in real-world clinical practice. This study aims to characterize the hepatitis C virus cascade of care and identify the factors associated with hepatitis C virus testing and diagnosis among Florida Medicaid beneficiaries with substance use disorders.

Assigning uncertainties in the inversion of NMR relaxation data.

Recovering the relaxation-time density function (or distribution) from NMR decay records requires inverting a Laplace transform based on noisy data, an ill-posed inverse problem. An important objective in the face of the consequent ambiguity in the solutions is to establish what reliable information is contained in the measurements. To this end we describe how upper and lower bounds on linear functionals of the density function, and ratios of linear functionals, can be calculated using optimization theory.

Resolving quadrature fringes in real time.

In many interferometers, two fringe signals can be generated in quadrature. The relative phase of the two fringe signals depends on whether the optical path length is increasing or decreasing. A system is developed in which two quadrature fringe signals are digitized and analyzed in real time with a digital signal processor to yield a linear, high-resolution, wide-dynamic-range displacement transducer.