Detection of urinary gonadotropins in callitrichid monkeys with a sensitive immunoassay based upan a unique monoclonal antibody.

A radioimmunological method for measuring urinary luteinizing hormone (LH) and chorionic gonadotropin (CG) excretion in the family Callitrichidae is described. The method uses a monoclonal antibody that will be available in virtually unlimited quantity. Several polyclonal antisera that have been useful for the detection of callitrichid gonadotropins are near depletion.

The secretion of bioactive and immunoreactive follicle-stimulating hormone (FSH) and luteinizing hormone (LH) throughout the menstrual cycle of the rhesus monkey (Macaca mulatta).

The present study provides the first evaluation of related changes in serum levels of bioactive FSH (Bio FSH) and immunoreactive FSH (iFSH), and concurrent dynamics of LH and FSH bioactivity throughout the menstrual cycle of the rhesus monkey. Mean concentrations of Bio FSH were elevated on days 0 and 1 (n = 7; P < 0.05; day 0 = preovulatory LH surge).

Biochemical and biological properties of urinary follicle-stimulating hormone (FSH) from the rhesus monkey (Macaca mulatta).

Follicle-stimulating hormone (FSH) is routinely used for the induction of superovulation in women. Homologous gonadotropin preparations that could be used for reproductive studies in macaques would have valuable research applications. Accordingly, we set out to characterize the physical and biological characteristics of urinary FSH (UFSH) in the ovariectomized rhesus monkey.