Prevention of recurrent affective episodes using extinction training in the reconsolidation window: A testable psychotherapeutic strategy.

Stressors may initially precipitate affective episodes, but with sufficient numbers of recurrences, episodes can occur more autonomously. It is postulated the memory engram for these recurrent depressions moves from the conscious representational memory system to the unconscious habit memory system encoded in the striatum. If this were the case, cognitive behavior therapy targeted toward extinction of habit memories could be an effective maneuver for helping reverse the automaticity of affective episode recurrence.

Immunity-to-change: are hidden motives underlying patient nonadherence to chronic disease medications?

New approaches to understanding patient nonadherence to chronic disease medications are urgently needed. To explore whether patient hidden motives and their underlying assumptions contribute to nonadherence, we examined an innovative application to health care of a transformative learning process successfully used in work settings, immunity-to-change. Eligible participants taking at least 2 chronic disease medications, filling prescriptions at U.

Questioning the "big assumptions". Part II: recognizing organizational contradictions that impede institutional change.

Background: Well-designed medical curriculum reforms can fall short of their primary objectives during implementation when unanticipated or unaddressed organizational resistance surfaces. This typically occurs if the agents for change ignore faculty concerns during the planning stage or when the provision of essential institutional safeguards to support new behaviors are neglected. Disappointing outcomes in curriculum reforms then result in the perpetuation of or reversion to the status quo despite the loftiest of goals.

Questioning the "big assumptions". Part I: addressing personal contradictions that impede professional development.

Background: The ultimate success of recent medical curriculum reforms is, in large part, dependent upon the faculty's ability to adopt and sustain new attitudes and behaviors. However, like many New Year's resolutions, sincere intent to change may be short lived and followed by a discouraging return to old behaviors. Failure to sustain the initial resolve to change can be misinterpreted as a lack of commitment to one's original goals and eventually lead to greater effort expended in rationalizing the status quo rather than changing it.