Publications by authors named "Robert J Lapidus"

Article Synopsis
  • - Nebulized formoterol fumarate (FFIS) is a long-acting bronchodilator alternative for COPD patients who struggle with handheld devices, showing significant bronchodilation effects within 5 minutes of administration.
  • - In a 12-week trial with 351 COPD subjects, FFIS significantly improved lung function (FEV1) and quality of life scores compared to placebo, with no signs of tolerance development.
  • - FFIS had a comparable safety and efficacy profile to another inhaled treatment (Foradil Aerolizer), with the most common side effects being dry mouth, nausea, and insomnia.
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Introduction: Ipratropium bromide (IB) is an established and effective first-line maintenance treatment for patients with chronic obstructive pulmonary disease (COPD). A new IB metered-dose inhaler (MDI) using hydrofluoroalkane 134a propellant (IB HFA) has been developed as an alternative to the MDI containing chlorofluorocarbon (IB CFC).

Objective: To compare the long-term safety and efficacy of IB HFA and IB CFC in patients with COPD.

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