Publications by authors named "Robert J Chambers"

Article Synopsis
  • * Biodegradable bioplastic membranes, made from a mix of thermoplastic polyurethane (TPU) and polylactic acid (PLA), offer strength and effectiveness while decomposing under specific conditions.
  • * These electrospun membranes provide good air filtration and significantly reduce reliance on petroleum-based materials while addressing plastic waste through biodegradability.
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The fabrication of pressure-sensitive adhesives (PSA) using liquid crystal elastomers (LCE) that are tolerant to substrate roughness is explored in this work. Traditional soft adhesives are designed by maintaining a balance between their cohesive strength and compliance. However, rough surfaces can significantly affect the adhesion strength of PSAs.

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Oxindole (2) is a potent and selective PDE2 inhibitor with a favorable ADME, physiochemical and pharmacokinetic profile to allow for use as a chemical tool in elucidating the physiological role of PDE2.

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Nicotinamide (2) is a potent and selective inhibitor of the PDE4D isozyme and as a chemical tool selectively blocks eosinophil mediator release and chemotaxis thus linking the role of PDE4D to eosinophil function.

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