Publications by authors named "Robert Gornall"
Objective: The aim of this study was to develop a predictive model for risk of death in hospital for gynecological cancer patients specifically examining the impact of sociodemographic factors and emergency admissions to inform patient choice in place of death.
Methods: The model was based on data from 71,269 women with gynecological cancer as underlying cause of death in England, January 1, 2000, to July 1, 2012, in a national Hospital Episode Statistics-Office for National Statistics database. Two thousand eight hundred eight deaths were used for validation of the model.
Article Synopsis
- Vulval lichen sclerosus (LS) is an inflammatory condition that can increase the risk of vulval cancer, requiring accurate diagnosis which can sometimes necessitate biopsies.
- Raman spectroscopy shows promise as a non-invasive diagnostic tool that could help distinguish LS from other vulval issues in real-time, potentially minimizing the need for biopsies.
- In a study with 27 women, Raman spectroscopy demonstrated a diagnostic accuracy with 91% sensitivity and 80% specificity for identifying LS, suggesting it may be effective for clinical use pending further research.
Article Synopsis
- - A 34-year-old woman with no previous pregnancies and a history of high-grade cervical dyskaryosis sought treatment to start a family after undergoing multiple cervical excisions.
- - She underwent a simple vaginal trachelectomy along with an isthmic cerclage to remove abnormal cervical tissue while minimizing risks to her future pregnancies.
- - Six months after surgery, she tested negative for issues, became pregnant naturally, experienced a health scare in her pregnancy, but ultimately delivered a healthy baby via cesarean section at 37 weeks.
Objective: Endometrial cancer is classified into: Type I estrogen-dependent endometrioid adenocarcinoma, with good prognosis and type 2 non-estrogen-dependent cancer with serous or clear cell histology and poor prognosis. Grade 3 endometrioid cancers (G3 EEC), share features of type 1 and type 2 cancer and have not been classified as either. This study compares immunohistochemistry and survival in G3 EEC and type 2 cancers.
View Article and Find Full Text PDFThis review presents key advances in the management of cervical cancer. Traditionally, cervical cancer is staged clinically and has been treated either by radical hysterectomy or by radiotherapy. Improvements in imaging have led to more accurate therapeutic decision making and treatment planning.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed data from 100 women with Stage I endometrial cancer, focusing on the effects of omental biopsy in diagnosing extrapelvic disease.* -
- Out of the participants, 80 underwent an omental biopsy, with six cases showing adenocarcinoma in the omentum; no significant complications were reported from the procedure.* -
- The findings suggest that visual inspection and biopsy of the omentum during surgery can reveal more extensive disease, potentially changing treatment plans for around 10% of patients who may need additional pelvic radiation.*