Publications by authors named "Robert Gombar"
COVID-19 has been a global public health and economic challenge. Screening for the SARS-CoV-2 virus has been a key part of disease mitigation while the world continues to move forward, and lessons learned will benefit disease detection beyond COVID-19. Saliva specimen collection offers a less invasive, time- and cost-effective alternative to standard nasopharyngeal swabs.
View Article and Find Full Text PDFSpinal muscular atrophy (SMA) is a human genetic disorder characterized by muscle weakness, muscle atrophy, and death of motor neurons. SMA is caused by mutations or deletions in a gene called (). is a housekeeping gene, but the most prominent pathologies in SMA are atrophy of myofibers and death of motor neurons.
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- Daphnia pulex is crucial for aquatic ecosystems and serves as a key model for ecological and evolutionary studies, but its proteome has not been fully characterized due to challenges in sample preparation and a focus on genome analysis.
- Various methods of sample handling and mass spectrometry were tested in this study to enhance the exploration of D. pulex proteins, leading to better results when using both in-gel and in-solution trypsin digestion techniques.
- The findings reveal enriched mitochondrial and hydrolytic functions in D. pulex and identified new proteins that may affect genome modification, with data accessible through ProteomeXchange (PXD008455).
Unlabelled: Chinook salmon (Oncorhynchus tshawytscha) are external fertilizers that display sneak-guard alternative reproductive tactics. The larger hooknose males dominate mating positions, while the smaller jack males utilize sneak tactics to achieve fertilization. Although poorly understood, previous studies have suggested that differences in spermatozoa quality may play a critical role in sperm competition.
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