Publications by authors named "Robert Frankenthaler"
Unlabelled: Wide local excision (WLE) with a safety margin is the standard of treatment for primary head and neck cutaneous malignant melanoma (HNCMM). Studies have demonstrated inconsistency in recurrence rates following immediate versus delayed reconstruction. The objectives of this study were to assess and compare recurrence rates after WLE of HNCMM followed by immediate or delayed reconstruction in determining recurrence-free survival estimates.
View Article and Find Full Text PDFCarotid body tumors (CBT) are rare neuroendocrine neoplasms that usually present in the third or fourth decades of life and are benign in more than 95% of cases. In the angiographic literature, the arterial supply to carotid body tumors is well documented but is often incomplete, with infrequent mention of the glomic artery, a common arterial feeder described in the anatomic and pathologic literature. Through a review of our neuroendovascular patient database, we identified eight patients with CBT undergoing transarterial embolization followed by resection.
View Article and Find Full Text PDFObjective: Assess impact of reconstructive procedures on patients undergoing laryngopharyngectomy and to determine whether 30-day postoperative morbidity and mortality varied between patients who underwent flap reconstruction and those who did not.
Study Design: Retrospective analysis of the prospectively collected American College of Surgeons National Surgical Quality Improvement (ACS-NSQIP) database.
Setting: Tertiary medical center.
Objectives/hypothesis: To review the known histopathologic findings and clinical behavior of mammary analogue secretory carcinoma (MASC).
Data Sources: PubMed.
Review Methods: Literature search using the terms "Mammary analogue secretory carcinoma," "Mammary analog secretory carcinoma," and "MASC" to identify all relevant publications.
Free tissue transfer in the head and neck cancer patient with graft-versus-host disease.
J Otolaryngol Head Neck Surg
April 2009
Article Synopsis
- Melanomas with poorly defined borders and other challenging characteristics often require multiple surgeries for effective treatment.
- The use of reflectance mode confocal microscopy has emerged as a promising noninvasive diagnostic tool for accurately identifying pigmented lesions.
- In clinical cases, confocal microscopy not only aided in the diagnosis and treatment monitoring of amelanotic melanoma but also helped establish clear surgical margins in locally recurrent and lentigo maligna melanomas.
Background: The authors conducted a Phase I/II study in patients with a poor prognosis who had locally advanced squamous cell carcinoma of the head and neck (SCCHN) and who were treated initially with induction chemotherapy. Patients were treated with weekly docetaxel and concurrent daily fractionated radiation therapy to determine the maximum tolerated dose (MTD) of docetaxel and the efficacy of the regimen.
Methods: Twenty-two patients were enrolled, and 21 patients were treated.