Why do subcutaneous ports get stuck? A case-control study.

Purpose: We sought to identify clinical features associated with difficult subcutaneous port removals in children.

Methods: Ports placed between April 2014 and September 2017 at our institution were prospectively tracked for difficult removals. A case-control analysis was performed.

Neutropenia at the time of subcutaneous port insertion may not be a risk factor for early infectious complications in pediatric oncology patients.

Background: The risk of infection associated with subcutaneous port (SQP) placement in patients with neutropenia remains unclear. We reviewed the rate of early infectious complications (<30 days) following SQP placement in pediatric oncology patients with or without neutropenia [absolute neutrophil count (ANC) <500/mm].

Methods: Baseline characteristics and infectious complications were compared between groups using univariate and multivariate analyses.

Impact of tumor histology and grade on treatment success of percutaneous renal cryoablation.

Background: We analyzed oncological outcomes in patients who underwent percutaneous renal cryoablation (PRC) with documented renal cell carcinoma (RCC) by perioperative biopsy.

Methods: Multicenter retrospective analysis of 153 patients [median follow-up 48 months] who underwent PRC from 09/2005 to 08/2014 was performed. We divided the cohort into patients who developed recurrence versus no recurrence.

Initial diagnostic management of pediatric bone tumors.

Background: Osteosarcoma (OS) and the Ewing sarcoma family of tumors (ESFT) are the most common primary pediatric bone malignancies. We sought to assess the diagnostic accuracy of initial tumor biopsies in patients with OS or ESFT at a pediatric cancer center.

Methods: All biopsies performed at initial presentation of patients with OS or ESFT at our institution from 2003 to 2012 were retrospectively reviewed.

Distinguishing Osteomyelitis From Ewing Sarcoma on Radiography and MRI.

Objective: The purpose of this study was to determine whether clinical and imaging features can distinguish osteomyelitis from Ewing sarcoma (EWS) and to assess the accuracy of percutaneous biopsy versus open biopsy in the diagnosis of these diseases.

Materials And Methods: Three radiologists reviewed the radiographs and MRI examinations of 32 subjects with osteomyelitis and 31 subjects with EWS to determine the presence of 36 imaging parameters. Information on demographic characteristics, history, physical examination findings, laboratory findings, biopsy type, and biopsy results were recorded.

Safety and diagnostic accuracy of tumor biopsies in children with cancer.

Background: Tumor biopsies are central to the diagnosis and management of cancer and are critical to efforts in personalized medicine and targeted therapeutics. In the current study, the authors sought to evaluate the safety and accuracy of biopsies in children with cancer.

Methods: All biopsies performed in children at the study institution with a suspected or established diagnosis of cancer from 2003 through 2012 were reviewed retrospectively.

RENAL nephrometry score is associated with complications after renal cryoablation: a multicenter analysis.

Objective: To analyze outcomes and complications of percutaneous (PRC) and laparoscopic renal cryoablation (LRC) using the radius, endophytic, nearness to collecting system, anterior/posterior, and location (RENAL) nephrometry system.

Methods: Retrospective multicenter analysis of 154 consecutive patients who underwent either ultrasound-guided LRC (n = 88) or computed tomography (CT)-guided PRC (n = 66) from March 2003 to December 2011. RENAL score and demographics were compared to postoperative complications (Clavien).

MESSENGER observations of transient bursts of energetic electrons in Mercury's magnetosphere.

The MESSENGER spacecraft began detecting energetic electrons with energies greater than 30 kilo-electron volts (keV) shortly after its insertion into orbit about Mercury. In contrast, no energetic protons were observed. The energetic electrons arrive as bursts lasting from seconds to hours and are most intense close to the planet, distributed in latitude from the equator to the north pole, and present at most local times.

MESSENGER observations of extreme loading and unloading of Mercury's magnetic tail.

During MESSENGER's third flyby of Mercury, the magnetic field in the planet's magnetic tail increased by factors of 2 to 3.5 over intervals of 2 to 3 minutes. Magnetospheric substorms at Earth are powered by similar tail loading, but the amplitude is lower by a factor of approximately 10 and typical durations are approximately 1 hour.

MESSENGER observations of magnetic reconnection in Mercury's magnetosphere.

Solar wind energy transfer to planetary magnetospheres and ionospheres is controlled by magnetic reconnection, a process that determines the degree of connectivity between the interplanetary magnetic field (IMF) and a planet's magnetic field. During MESSENGER's second flyby of Mercury, a steady southward IMF was observed and the magnetopause was threaded by a strong magnetic field, indicating a reconnection rate ~10 times that typical at Earth. Moreover, a large flux transfer event was observed in the magnetosheath, and a plasmoid and multiple traveling compression regions were observed in Mercury's magnetotail, all products of reconnection.

Mercury's magnetosphere after MESSENGER's first flyby.

Observations by MESSENGER show that Mercury's magnetosphere is immersed in a comet-like cloud of planetary ions. The most abundant, Na+, is broadly distributed but exhibits flux maxima in the magnetosheath, where the local plasma flow speed is high, and near the spacecraft's closest approach, where atmospheric density should peak. The magnetic field showed reconnection signatures in the form of flux transfer events, azimuthal rotations consistent with Kelvin-Helmholtz waves along the magnetopause, and extensive ultralow-frequency wave activity.

MArs Neutron Energy Spectrometer (MANES): an instrument for the Mars 2003 Lander.

We describe the instrument design and detector development for MANES which has been selected to fly on the Mars 2003 Lander. Section 1 explains the need for the spectrometer in determining the increased risk of carcinogenesis for astronauts. Section 2 presents the instrument design including an outline drawing, a cross-sectional view and a detailed block diagram.