CLINICAL OUTCOMES AND TREATMENT COURSE OF EYES WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION FOLLOWING THE DEVELOPMENT OF ENDOPHTHALMITIS.

Purpose: To evaluate the clinical course of patients with neovascular age-related macular degeneration (nAMD) after developing endophthalmitis during their treatment with intravitreal injections.

Methods: Multicenter, retrospective series.

Results: From April 2013 to October 2018, 196,598 intravitreal anti-vascular endothelial growth factor (VEGF) injections were performed, with 75 cases of endophthalmitis (incidence 0.

The COMS Randomized Trial of Iodine 125 Brachytherapy for Choroidal Melanoma: IV. Local Treatment Failure and Enucleation in the First 5 Years after Brachytherapy. COMS Report No. 19.

Objective: To describe the frequency and predictors of local treatment failure and enucleation after iodine 125 (I) brachytherapy in patients with choroidal melanoma treated and followed up in a large randomized clinical trial.

Design: Prospective, noncomparative, interventional case series within a randomized, multicenter clinical trial.

Participants: Patients enrolled in the Collaborative Ocular Melanoma Study (COMS) trial of enucleation versus brachytherapy between February 1987 and July 1998; tumors measured 2.

Mortality after deferral of treatment or no treatment for choroidal melanoma.

Purpose: To report mortality of patients who were eligible for enrollment in the Collaborative Ocular Melanoma Study (COMS) clinical trials of medium-sized choroidal melanoma or large-sized choroidal melanoma but chose to defer treatment or receive no melanoma treatment.

Design: Prospective nonrandomized multicenter cohort study as an adjunct to COMS randomized clinical trials.

Methods: Patient follow-up procedures included examinations, correspondence, telephone contacts, and National Death Index searches.

Postoperative Hemorrhagic Occlusive Retinal Vasculitis: Expanding the Clinical Spectrum and Possible Association with Vancomycin.

Purpose: To describe a syndrome of hemorrhagic occlusive retinal vasculitis (HORV) that developed after seemingly uncomplicated cataract surgery.

Design: Retrospective case series.

Subjects: Eleven eyes of 6 patients from 6 different institutions.

Outcomes associated with ganciclovir implants in patients with AIDS-related cytomegalovirus retinitis.

Purpose: To investigate complications associated with ganciclovir implants used to treat AIDS-related cytomegalovirus (CMV) retinitis, and to identify factors that predict poor outcomes.

Design: Retrospective chart review.

Participants: Consecutive patients with AIDS-related CMV retinitis from 3 clinical facilities who underwent implantation procedures during the period January 1, 1995 through December 31, 2001.

Iris and anterior chamber angle neovascularization after iodine 125 brachytherapy for uveal melanoma.

Purpose: Iris neovascularization (INV) and anterior chamber angle neovascularization after radiotherapy for uveal melanoma may lead to neovascular glaucoma and enucleation. However, neovascularization of the anterior ocular segment may respond favorably to treatment with panretinal photocoagulation. The purpose of this study was to evaluate the frequency, interval to development, and predisposing factors of anterior ocular segment neovascularization following iodine 125 (I125) brachytherapy for uveal melanoma.

Functional anatomy of the anophthalmic socket: insights from magnetic resonance imaging.

Purpose: Changes in anophthalmic socket anatomy can significantly compromise esthetics and motility after enucleation. This study evaluated such changes by using magnetic resonance imaging (MRI) of enucleated and fellow orbits.

Methods: High-resolution, surface coil MRI was performed in five patients after enucleation for uveal melanoma.

Mortality after deferral of treatment or no treatment for choroidal melanoma.

Purpose: To report mortality of patients who were eligible for enrollment in the Collaborative Ocular Melanoma Study (COMS) clinical trials of medium-sized choroidal melanoma or large-sized choroidal melanoma but chose to defer treatment or receive no melanoma treatment.

Design: Prospective nonrandomized multicenter cohort study as an adjunct to the COMS randomized clinical trials.

Methods: Patient follow-up procedures included examinations, correspondence, telephone contacts, and National Death Index searches.

The COMS randomized trial of iodine 125 brachytherapy for choroidal melanoma: IV. Local treatment failure and enucleation in the first 5 years after brachytherapy. COMS report no. 19.

Objective: To describe the frequency and predictors of local treatment failure and enucleation after iodine 125 (I(125)) brachytherapy in patients with choroidal melanoma treated and followed up in a large randomized clinical trial.

Design: Prospective, noncomparative, interventional case series within a randomized, multicenter clinical trial.

Participants: Patients enrolled in the Collaborative Ocular Melanoma Study (COMS) trial of enucleation versus brachytherapy between February 1987 and July 1998; tumors measured 2.

Clear lens extraction with intraocular lens implantation during retinal detachment repair in patients with Acquired Immune Deficiency Syndrome (AIDS) [correction of autoimmune deficiency syndrome] and cytomegalovirus retinitis.

Objective: To assess the outcomes of clear lens extraction with intraocular lens (IOL) implantation during repair of retinal detachment by vitrectomy with silicone oil tamponade in patients with acquired immunodeficiency syndrome (AIDS) and cytomegalovirus (CMV) retinitis.

Design: Retrospective, noncomparative case series.

Participants: Twelve eyes of 10 patients with AIDS, CMV retinitis, and retinal detachment.