Burn wound conversion refers to the phenomenon whereby superficial burns that appear to retain the ability to spontaneously heal, convert later into deeper wounds in need of excision. While no current treatment can definitively stop burn wound conversion, attempts to slow tissue damage remain unsatisfactory, justifying the need for new therapeutic interventions. To attenuate burn wound conversion, various studies have targeted at least one of the molecular mechanisms underlying burn wound conversion, including ischemia, inflammation, apoptosis, autophagy, generation of reactive oxygen species, hypothermia, and wound rehydration.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
June 2022
Unlabelled: Prominent ears are a common congenital deformity of the head and neck. Correcting concha hypertrophy is an important step in otoplasty. Despite the risk of postoperative deformity due to the sharp edges created by excision, removing a section of cartilage is sometimes the only method to obtain a satisfying and long-lasting result.
View Article and Find Full Text PDFBurns disrupt the protective skin barrier with consequent loss of cutaneous temperature regulation, infection prevention, evaporative losses, and other vital functions. Chronically, burns lead to scarring, contractures, pain, and impaired psychosocial well-being. Several skin substitutes are available and replace the skin and partially restore functional outcomes and improve cosmesis.
View Article and Find Full Text PDFActive materials have been explored in recent years to demonstrate superluminal group velocities over relatively broad bandwidths, implying a potential path towards bold claims such as information transport beyond the speed of light, as well as antennas and metamaterial cloaks operating over very broad bandwidths. However, causality requires that no portion of an impinging pulse can pass its precursor, implying a fundamental trade-off between bandwidth, velocity and propagation distance. Here, we clarify the general nature of superluminal propagation in active structures and derive a bound on these quantities fundamentally rooted into stability considerations.
View Article and Find Full Text PDFThe exotic physics emerging in non-Hermitian systems with balanced distributions of gain and loss has recently drawn a great deal of attention. These systems exhibit phase transitions and exceptional point singularities in their spectra, at which eigen-values and eigen-modes coalesce and the overall dimensionality is reduced. So far, these principles have been implemented at the expense of precise fabrication and tuning requirements, involving tailored nano-structured devices with controlled optical gain and loss.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
October 2020
We demonstrate an optomechanical platform where optical mode conversion mediated by mechanical motion enables the arbitrary tailoring of polarization states of propagating light fields. Optomechanical interactions are realized in a Fabry-Pérot resonator, which naturally supports two polarization-degenerate states while an optical control field induces rotational symmetry breaking. Applying such principles, the entire Poincaré sphere is spanned by just optical control of the driving field, realizing reciprocal and nonreciprocal optomechanically induced birefringence for linearly polarized and circularly polarized control driving.
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