Assessing psychoactive pharmaceuticals and transitioning pharmacological fatigue countermeasures into operational environments.

Herein we summarize a discussion on the topic of how psychopharmaceuticals for potential military operational use may be evaluated based on their effects on performance and safety, and introduce two manuscripts: the first (Caldwell and Caldwell; 1) addressing the operational use of fatigue countermeasures; and the second (Rowland; 3) discussing the potential operational use and limitations of ketamine as a field analgesic. Fatigue countermeasures are usually employed by a relatively small number of military members engaged in sustained or continuous operations when sleep is not an option. Clinical treatments are available at any time as required to treat medical conditions.

Generating performance test batteries relevant to specific operational tasks.

The present review focuses on the development of a performance battery generation system that selects performance tests most applicable to particular jobs. First, a list or taxonomy of cognitive and performance skills that are involved in real-world jobs or missions is developed. Based on this list, an "armory" of performance tests probing those skills is identified.