Value of a simple measure of estrogen status for improving the diagnosis of coronary artery disease in women.

Purpose: To determine the potential impact of estrogen status on the pretest and postexercise test diagnostic accuracy of exercise testing.

Patients And Methods: The study comprised a total of 234 women and 326 men who underwent exercise testing followed by coronary angiography. We performed incremental logistic regression analysis of pretest (age, symptoms, smoking, diabetes, cholesterol level) with and without estrogen status (defined according to menopausal and oral estrogen status) and exercise test (two ST-segment and three non-ST-segment) variables separately for men and women.