Publications by authors named "Robert Clive Landis"
Article Synopsis
- Mosquitoes act as crucial carriers for viruses and can mix different viruses through co-infection, leading to new viral strains.
- A study collected various mosquito species from locations in central Europe and the Caribbean to analyze their viral content using advanced sequencing techniques.
- Researchers found a rich variety of viruses, particularly novel circular Rep-encoding single-stranded (CRESS) DNA viruses, including a new species and a potentially zoonotic virus, enhancing the understanding of viral diversity in these important vectors.
The process of inflammation is orchestrated by macrophages, according to their state of differentiation: thus, classically activated (M1) macrophages initiate the process by elaborating proinflammatory cytokines and reactive oxygen species, whereas the latter phase is controlled by alternatively activated macrophages (M2) to resolve inflammation and promote tissue remodelling with the release of growth factors. In a simple human inflammatory response, such as acute crystal arthropathy, macrophages progress linearly through M1 and M2 phases; however, in chronic inflammatory responses, such as atherosclerosis and Diabetic Nephropathy (DN), both M1 and M2 macrophages may coexist, leading to persistent inflammation and fibrosis. A key macrophage receptor that regulates conversion from M1 to M2 is CD163, the hemoglobin scavenger receptor.
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