A woman in her 40s, with a known history of fibromyalgia, presented with high-grade fever and constitutional symptoms occurring 5 days following vaccination with Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1). Her inflammatory markers and neutrophil count were found to be elevated and as such, she was started on antibiotics. Despite treatment, markers remained elevated and temperature spikes persisted for another 4 weeks before these symptoms subsided, and her blood tests normalised.
View Article and Find Full Text PDFBackground: Diagnosis of acute poisoning in patients with altered mental status and absent history is a challenging diagnostic problem in clinical practice.
Objective: The aims of the study were to develop a simple clinical tool to stratify risk of acute poisoning in patients with altered mental states and no history of alcohol/drug ingestion, and develop a prediction model using initial observations from which a simple risk score could be derived.
Methods: The study was carried out on non-trauma patients aged 15 years and older admitted with altered mental states and no history of alcohol or drug ingestion.
Background: Management of acute poisoning depends on the reliability of history of the poisoning event.
Objective: The objective of this study was to perform a meta-analysis from published data to determine summary measures of reliability of history in suspected acute poisoning.
Method: Relevant studies were selected from a search on the Medline database to perform a meta-analysis to calculate pooled estimates of κ statistic for agreement between history of poisoning and laboratory diagnosis.