Publications by authors named "Robert C Holladay"

Primary pulmonary T-cell lymphoma is an unusual subtype of peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). This is a general term used to describe a diverse group of T-cell-type lymphomas that would otherwise not be classified as a PTCL. Among non-Hodgkin's lymphomas, PTCL accounts for 12% of cases.

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Article Synopsis
  • A multicenter trial assessed the Spiration Valve System (SVS) against standard medical care for treating severe emphysema in patients aged 40 and older.
  • The study found that the SVS led to significant improvements in lung function (FEV) and other health measures after 6 and 12 months, although it increased the risk of serious adverse events, particularly pneumothorax.
  • Overall, while SVS showed effective results for managing severe emphysema, the safety concerns highlighted the need for careful patient monitoring.
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Lung nodules are being increasingly detected, particularly with lung cancer screening with low-dose computed tomography. Although the vast majority of lung nodules are benign, many often require tissue diagnosis. Several modalities to obtain diagnostic tissue from peripheral lung nodules are available.

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Background And Objective: The development of novel technologies has increased the yield from transbronchial biopsies while preserving patient safety by guiding biopsies to the area of interest. Other technologies have helped identify pre-cancerous or sessile lesions in the endobronchial space by utilizing interactions between tissue and light at varying wavelengths. Probe-based confocal laser endomicroscopy (pCLE) is a new technology that encompasses the benefits of both guided biopsies and novel optical imaging in one device.

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