Local seed displacement from Day 0 to Day 30 in I-125 permanent prostate brachytherapy: A detailed, computed tomography-based analysis.

Purpose: To accurately quantify local seed displacement from Day 0 to Day 30 for our brachytherapy procedure. To quantify seed loss/migration and to identify the locations from where seeds are missing.

Methods And Materials: Seed displacements were analyzed in 62 consecutive patients, who received brachytherapy with stranded I-125 seeds.

Dosimetric impact of contouring and image registration variability on dynamic I prostate brachytherapy.

Purpose: The quality of permanent prostate brachytherapy can be increased by addition of imaging modalities in the intraoperative procedure. This addition involves image registration, which inherently has inter- and intraobserver variabilities. We sought to quantify the inter- and intraobserver variabilities in geometry and dosimetry for contouring and image registration and analyze the results for our dynamic I brachytherapy procedure.

Cone-beam CT-based adaptive planning improves permanent prostate brachytherapy dosimetry: An analysis of 1266 patients.

Purpose: To evaluate adaptive planning for permanent prostate brachytherapy and to identify the prostate regions that needed adaptation.

Methods And Materials: After the implantation of stranded seeds, using real-time intraoperative planning, a transrectal ultrasound (TRUS)-scan was obtained and contoured. The positions of seeds were determined on a C-arm cone-beam computed tomography (CBCT)-scan.