Publications by authors named "Roben Soheili"
The Zika virus (ZIKV) is classified within the Flavivirus genus of the Flaviviridae family and is categorized as an arbovirus. The virus was initially identified in a rhesus monkey in Uganda in 1947 and later in a human in Nigeria in 1952. Since 2007, the prevalence of the virus has been on the rise, culminating in a major outbreak in the United States (US) in 2015.
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- The influenza virus (IFV) is a significant global health concern that affects both health systems and economies, highlighting the need to understand how it causes disease.
- Ferroptosis, a specific type of cell death linked to iron and lipid damage, plays a role in the body's response to IFV and influences inflammation during the infection.
- Investigating how ferroptosis works in the context of IFV could lead to new drug treatments that use ferroptosis inhibitors to combat viral infections effectively.
Background: Influenza infection is highly contagious respiratory illness triggered by the influenza virus, bearing substantial implications for global health. Influenza B viruses, specifically the Victoria and Yamagata lineages, have contributed to the disease burden, and the mismatch between circulating strains and vaccine strains has led to increased mortality and economic costs. Understanding the global epidemiology, seasonal variations, and genetic characteristics of influenza B is crucial for effective prevention and control strategies.
View Article and Find Full Text PDFAdult T-cell leukemia/lymphoma (ATLL), an infrequent malignancy resultant from human T-cell lymphotropic virus type I (HTLV-1), exhibits a spectrum of phenotypes, encompassing acute, smoldering, lymphomatous, and chronic variants, each bearing distinct clinical presentations. The preponderant acute manifestation is characterized by hypercalcemia, systemic manifestations, organomegaly, and dermatological eruptions. Conversely, the chronic phenotype is typified by lymphocytosis and/or cutaneous eruptions, while smoldering ATLL assumes an asymptomatic course.
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- * They can become resistant to treatments like chemotherapy and immunotherapy by using specific mechanisms to evade destruction, but when activated correctly, they can also fight cancer cells effectively.
- * The presence of macrophages in tumors is linked to poorer outcomes for patients, but they are being studied as potential targets for new cancer therapies, especially for melanoma, colon, glioma, and breast cancers.