Melting ice and rising seas - connecting projected change in Antarctica's ice sheets to communities in Aotearoa New Zealand.

Changes in global mean sea level are a clear indicator of a warming climate, but local factors including land subsidence or uplift, cause changes in relative sea level that drive shoreline shifts. These local changes and their impact on coastal hazards matter to coastal communities. NZ SeaRise produced relative sea level projections for Aotearoa to include the latest global climate and Antarctic Ice Sheet research and estimates of vertical land movement at high spatial resolution.

Global survey shows planners use widely varying sea-level rise projections for coastal adaptation.

Including sea-level rise (SLR) projections in planning and implementing coastal adaptation is crucial. Here we analyze the first global survey on the use of SLR projections for 2050 and 2100. Two-hundred and fifty-three coastal practitioners engaged in adaptation/planning from 49 countries provided complete answers to the survey which was distributed in nine languages - Arabic, Chinese, English, French, Hebrew, Japanese, Korean, Portuguese and Spanish.

Anxiolytic-like effects observed in rats exposed to the elevated zero-maze following treatment with 5-HT2/5-HT3/5-HT4 ligands.

The present study examined the effects of administering selective 5-HT antagonists and agonists to rats tested in the elevated zero-maze (EZM) model of anxiety. The EZM paradigm has advantages over the elevated plus-maze (EPM) paradigm with respect to measuring anxiety, yet has been utilized less frequently. Three experiments were conducted each with a diazepam control (0.

Revisiting the serotonin-aggression relation in humans: a meta-analysis.

The inverse relation between serotonin and human aggression is often portrayed as "reliable," "strong," and "well established" despite decades of conflicting reports and widely recognized methodological limitations. In this systematic review and meta-analysis, we evaluate the evidence for and against the serotonin deficiency hypothesis of human aggression across 4 methods of assessing serotonin: (a) cerebrospinal fluid levels of 5-hydroxyindoleacetic acid (CSF 5-HIAA), (b) acute tryptophan depletion, (c) pharmacological challenge, and (d) endocrine challenge. Results across 175 independent samples and over 6,500 total participants were heterogeneous, but, in aggregate, revealed a small, inverse correlation between serotonin functioning and aggression, anger, and hostility (r = -.

Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics.

Cardiolipin is a class of mitochondrial specific phospholipid, which is intricately involved in mitochondrial functionality. Differences in cardiolipin species exist in a variety of tissues and diseases. It has been demonstrated that the cardiolipin profile is a key modulator of the functions of many mitochondrial proteins.

Aggression after traumatic brain injury: analysing socially desirable responses and the nature of aggressive traits.

Primary Objective: To compare patients with traumatic brain injury (TBI) with controls on sub-types of aggression and explore the role of social desirability.

Design: Quasi-experimental, matched-participants design.

Methods And Procedures: Sixty-nine participants were included in the study.