Publications by authors named "Roa Alsajjan"

Glioblastoma is the most common malignant primary brain tumor in adults. The prognosis is extremely poor even with standard treatment of maximal safe resection, radiotherapy, and chemotherapy. Recurrence is inevitable within months, and treatment options are very limited.

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Article Synopsis
  • Single-cell technologies have improved our understanding of the tumor microenvironment by showing significant diversity among tumor cells and their surroundings.
  • This study used imaging mass cytometry to analyze over 1.1 million cells from various high-grade glioma and brain metastasis tumors, providing insights into immune landscapes and activation states.
  • The research identified specific myeloperoxidase-positive macrophages linked to better survival rates in glioblastoma patients, highlighting the importance of spatial resolution in single-cell studies for understanding cancer biology.
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Background: Depression literacy in general population constitutes an ability to understand depression, with knowledge of disease, its risk factors and symptoms. High levels of depression literacy promote early intervention, potentially reducing related disability.

Aim: This study investigated the depression literacy in women visitors to clinics of a tertiary care hospital in Riyadh, Saudi Arabia.

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