Virological Characterization of Dual HIV-1/HIV-2 Seropositivity and Infections in Southern Ghana.

Summary Background: Dual HIV-1/HIV-2 seropositivity (dual seropositivity) is common in West African countries including Ghana. The diagnosis of dual HIV-1/HIV-2 infections is however complicated as HIV-2 DNA is more often not detected in dual seropositive individuals.

Objectives: To detect the presence of HIV-1 and HIV-2 pro-viral DNA in dual seropositives and to determine the correlation between HIV-2 antibody titers and presence of HIV-2 DNA.

Impairment of renal sodium excretion in tropical residents--phenomenological analysis.

There is evidence of impaired renal sodium excretion in salt-sensitive African Blacks. A decreased rate of renal sodium chloride (NaCl) excretion, low plasma renin activity and a tendency to elevated blood pressure are the hallmarks of salt sensitivity. Recent evidence indicates that increased proximal and distal tubular fluid reabsorption in some tropical residents may explain the impaired sodium excretion in these people.

Blackwater fever and acute renal failure in expatriates in Africa.

From September 1976 to July, 1993, 7 patients---5 Europeans, 1 Filipino national, and 1 Korean---were admitted to the Renal Unit of Korle Bu Teaching Hospital in Ghana with acute renal failure due to severe malaria and intravascular hemolysis. All these patients had been in the Tropics 3 to 8 weeks and none were no malarial prophylaxis. All needed dialysis because of severe uremic symptoms.

Hemodialysis in the treatment of acute renal failure in tropical Africa: a 20-year review at the Korle Bu Teaching Hospital, Accra.

From 1972 to 1992, 170 patients with acute renal failure (87 M, 83 F; mean age 32.51 +/- SE 0.945) underwent hemodialysis at the renal unit of the Korle Bu Teaching Hospital, Accra.

Anuric acute renal failure due to bilateral accidental ureteric ligation during abdominal hysterectomy.

Objective: To determine the incidence of accidental ureteric ligation causing acute anuric renal failure (AARF) at the KorleBu Teaching Hospital, Accra, Between August 1984 and December 1991.

Method: The records and operative data of all cases managed with acute anuric renal failure at the hospital during the period were reviewed.

Result: The 7 patients with AARF presented with mean pre-referral anuria of 3.