Publications by authors named "Rizzo J"

Background: Junctional hemorrhage is a leading cause of battlefield death. Multiple FDA-approved junctional tourniquet (JTQ) models demonstrate effective hemorrhage control in laboratory settings. However, there are few real-world use cases within the literature.

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Objectives: Studies comparing police, privately owned vehicle (POV), and ground Emergency Medical Services (GEMS) trauma transports reveal mixed results. It remains unclear whether using nonstandard transport methods may be beneficial in the setting of certain injuries. We sought to determine 24-h survival after transport by police or POV when compared to GEMS.

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Background: Whole blood (WB) resuscitation has been shown to provide mortality benefit. However, the impact of whole blood transfusions on the risk of venous thromboembolism (VTE) remains unclear. We sought to compare the VTE risk in patients resuscitated with WB vs component therapy (COMP).

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  • Systemic immune system abnormalities may play a role in rosacea development, with studies indicating a higher presence of abnormal bacteria and small intestinal bacterial overgrowth (SIBO) in affected individuals, though inconsistent testing has led to discrepancies in findings.* -
  • This study aimed to accurately assess the prevalence of abnormal bacteria and SIBO in individuals with rosacea while controlling for potential confounding factors, excluding those with gastrointestinal diseases or significant health issues.* -
  • Findings showed that 14.8% tested positive for abnormal bacteria and 33.3% for SIBO, with a notably higher SIBO rate in the rosacea cohort compared to the general population, suggesting a possible link between SIBO and ros
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Background: Visual disability is a growing problem for many middle-aged and older adults. Conventional mobility aids, such as white canes and guide dogs, have notable limitations that have led to increasing interest in electronic travel aids (ETAs). Despite remarkable progress, current ETAs lack empirical evidence and realistic testing environments and often focus on the substitution or augmentation of a single sense.

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Background: Health and healthcare disparities for surgical patients with blindness and low vision (pBLV) stem from inaccessible healthcare systems that lack universal design principles or, at a minimum, reasonable accommodations (RA).

Objectives: We aimed to identify barriers to developing and implementing RAs in the surgical setting and provide a review of best practices for providing RAs.

Methods: We conducted a search of PubMed for evidence of reasonable accommodations, or lack thereof, in the surgical setting.

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Background: Treatment for large burn injuries relies on adequate fluid resuscitation secondary to the severe systemic inflammatory response. With improved critical care and better understanding of the complications of over and under resuscitation, morbidity and mortality rates are decreasing. Neurologic complications are not often considered as an over-resuscitation complication after burn injury but may be considered an additional form of compartment syndrome-intracranial compartment syndrome; however, it has not been evaluated for a possible threshold similar to the Ivy Index for abdominal compartment syndrome.

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Background: Patients with disabilities face widespread barriers to accessing surgical care given inaccessible health systems, resulting in poor clinical outcomes and perpetuation of health inequities. One barrier is the lack of education, and therefore awareness, among trainees/providers, of the need for reasonable accommodations for surgical patients with disabilities.

Methods: We conducted a scoping review of the literature on the current state of disabilities curricula in medical education and graduate residency curriculum.

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Traumatic brain injuries (TBI) are common in dogs and cats that have sustained head trauma from a variety of causes. In moderate to severe TBI, damage from both the primary and secondary injuries can be life-threatening. TBI management may be further complicated by concurrent injuries in polytrauma patients.

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To describe an atypical presentation of vitreous inflammation in a patient with malignant hypertension. A case was evaluated. A patient presenting with a hypertensive emergency was found to have decreased vision in the setting of severe optic nerve head edema, extensive hard exudates, cotton-wool spots, and Elschnig spots in both eyes secondary to malignant hypertension as well as vitreous cells bilaterally.

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  • The study investigates calcium imbalances in soldiers injured during combat, focusing on their occurrence in emergency departments and their relation to other health issues and mortality within 24 hours.
  • Out of 941 military casualties, 26% exhibited calcium abnormalities, with hypocalcemia being more common (22%) than hypercalcemia (5%).
  • Patients with calcium derangements had lower injury severity scores and a higher survival rate in the hospital compared to those without derangements, although 24-hour survival rates were similar.
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  • Topical wound care after burns has changed how injuries are treated by using dressings that help prevent infections and promote healing while considering factors like pain and dressing change frequency.
  • This study looked at pain levels and opioid use related to different wound dressings, such as silver sulfadiazine, manuka honey, and negative-pressure wound therapy.
  • Results showed silver sulfadiazine typically resulted in lower pain scores and less opioid use compared to other dressings, suggesting the need for more detailed studies to better understand their impacts on pain management.
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Objectives: We seek to describe the current practice pattern use of prothrombin complex concentrate (PCC) and fibrinogen concentrate (FC) in trauma patients.

Background: Trauma-induced coagulopathy (TIC) and endotheliopathy of trauma (EOT) contribute significantly to mortality from traumatic haemorrhage. FC, and 4-factor PCC are potential treatments for EOT and TIC, respectively.

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  • A study investigated the use of resuscitative endovascular balloon occlusion of the aorta (REBOA) for managing severe torso trauma in emergency departments, highlighting its controversial role and limited data on patient outcomes.
  • The analysis included 3,398 REBOA procedures from 2017 to 2022, mostly involving male patients with an average age of 40, primarily stemming from collision injuries.
  • The findings showed that while survival rates were high (85%) shortly after REBOA placement, they declined significantly to 42% by discharge, indicating room for improvement in patient selection and outcomes.
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Background: The risks associated with blood product administration and venous thromboembolic events remains unclear. We sought to determine which blood products were associated with the development of deep vein thrombosis (DVT) and pulmonary embolism (PE).

Methods: We analyzed data from patients ≥18 years of age in the Trauma Quality Improvement Program (TQIP) database that received ≥1 blood product and survived ≥24 ​h.

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UNav is a computer-vision-based localization and navigation aid that provides step-by-step route instructions to reach selected destinations without any infrastructure in both indoor and outdoor environments. Despite the initial literature highlighting UNav's potential, clinical efficacy has not yet been rigorously evaluated. Herein, we assess UNav against standard in-person travel directions (SIPTD) for persons with blindness or low vision (PBLV) in an ecologically valid environment using a non-inferiority design.

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Non-invasive proxies, such as fur and feathers, are likely to be increasingly used to assess the potential exposure of chemicals, including trace metals and metalloids. However, the amount of external contamination is usually unknown, and there is no standard method for removing external contamination of trace metals in fur or feathers. To date, 40 % of studies published related to the measurement of trace metal levels in fur or the hair of non-human mammals and 24 % of studies in feathers do not state any washing methods or did not wash the samples before analysis.

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Immune effector cell (IEC) therapy represents a transformative advancement in oncology, leveraging the immune system to combat various malignancies. This article outlines a comprehensive framework for establishing and maintaining quality standards in IEC therapy amidst rapid scientific and clinical advancements. We emphasize the integration of structured process measures, robust quality assurance, and meticulous outcome evaluation to ensure treatment efficacy and safety.

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Penetrating orbital trauma from marine creatures, especially needlefish, should be considered after injuries sustained in open water. Advances in endoscopic sinus surgery have enabled surgeons to remove certain orbital foreign bodies through endoscopic endonasal approaches. 3D segmentation is a valuable pre-operative tool in complex endoscopic orbital cases.

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Importance: Mental health (MH) issues in children with cerebral palsy (CP) are poorly understood compared with other pediatric populations.

Objective: To examine MH diagnosis code assignment among children and young adults with CP and compare with typically developing (TD) and chronic condition (CC) pediatric populations.

Design, Setting, And Participants: This case-control study used International Statistical Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes to create a CP case set and CC and TD control sets using electronic health record data of children and young adults from a large tertiary care children's hospital in the midwestern United States between 2010 and 2022.

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