Perioperative Intravenous Lidocaine Infusion for Postlaparoscopic Cholecystectomy Pain.

Objective: To compare intravenous lidocaine infusion adjunct to NSAID and Acetaminophen with regular analgesics for postoperative mean pain score and mean ambulation time after laparoscopic cholecystectomy.

Study Design: Randomised controlled trial.

Place And Duration Of Study: Department of General Surgery, Islamabad Medical Complex, (IMC), from March 2020 to December 2021.

Drug-induced duodenal perforation in the paediatric patient with thalassemia major, an unreported side effect of iron- chelating agent: A case report.

Duodenal ulcer disease is uncommon in paediatric age group. Its perforation is even rarer. However, it should be kept in mind when examining children with acute abdomen especially if there are signs of shock or possibility of upper gastrointestinal bleed.

Adult Retroperitoneal Mature Cystic Teratoma Masquerading as Non-Endocrine Primary Adrenal Tumor.

Teratomas belong to non-seminomatous germ cell tumors and originate from totipotent germ cells. They are mostly made up of tissues derived from all three layers, i.e.

Adult Necrotising Enterocolitis in a Breast Cancer Patient after First Cycle of Adjuvant Chemotherapy.

Chemotherapy-induced diarrhea has become a worrisome problem for the patients as well as the treating surgeons and oncologists because patient outcome is significantly affected. Necrotising enterocolitis is a rare disease in adults. It is now termed as neutropenic enterocolitis in adults, because it is seen more often as a complication of aggressive systemic chemotherapy.

30-Day Readmission Rate and its Causes in General Surgical Patients.

Objective: To find out the 30-day readmission rate for different surgical procedures and determine the causes for readmissions.

Study Design: An audit report.

Place And Duration Of Study: Department of Surgery, The Aga Khan University Hospital, Karachi, in the calendar year 2014.

Improving Outcomes of Emergency Bowel Surgery Using NELA Model.

Objective: To find outcomes of emergency bowel surgery and review the processes involved in the care of these patients on the same template used in National Emergency Laparotomy Audit (NELA).

Study Design: An audit.

Place And Duration Of Study: Surgery Department, The Aga Khan University Hospital, Karachi, from December 2013 to November 2014.

Better outcome of splenectomy in younger patients suffering from chronic immune thrombocytopenia (ITP).

Immune thrombocytopenia purpura (ITP) may need splenectomy after failure of medical treatment. The aim of this study was to explore the outcome of splenectomy in chronic ITP and to point out factors which can predict better response to splenectomy. This retrospective chart review was conducted at the Aga Khan University Hospital, Karachi, and comprised adult patients who underwent splenectomy for ITP from October 2005 to December 2015.

Diagnostic accuracy of CT scan in staging resectable esophageal cancer.

Introduction: CT scan is an important tool in staging of esophageal cancer. Survival can be improved by providing neoadjuvant treatment which depends on stage of esophageal cancer. So it is very important to stage the disease accurately.

Short term outcome and predictors of response to neoadjuvant treatment in rectal cancer.

Objective: To evaluate response to neoadjuvant chemoradiation in the treatment of rectal cancer and to see if it can be predicted whether a particular patient will benefit from such treatment.

Methods: The retrospective case series was done at the Aga Khan University Hospital, Karachi, and comprised data related to period from January 2005 to December 2014 of patients with rectal cancer who had received neoadjuvant treatment. They were divided into responders and non-responders on the basis of imaging.

Valentino appendix: a report of 3 cases.

We present three cases of young male patients with perforated duodenal ulcer that were diagnosed and treated as appendicitis with appendectomy. They presented with peritonitis and were treated accordingly. Because of the misdiagnosis, their hospital course was significantly prolonged.

Factors affecting anastomotic leak after colorectal anastomosis in patients without protective stoma in tertiary care hospital.

Objective: To determine the factors associated with clinically significant anastomotic leak in patients having undergone large intestinal anastomosis.

Method: The retrospective study at the Aga Khan University Hospital, Karachi, comprised data between January 2000 and March 2010, related to patients who underwent colorectal anastomosis. Demographic details of the patients, as well as preop, intraop and postop risk factors were recorded.