HIF-1α regulated pathomechanism of low birth weight through angiogenesis factors in placental infection.

Background: Malaria in pregnancy leads to placental malaria. The primary pathogenesis of the complex fetal implications in placental malaria is tissue hypoxia due to sequestrations of -infected erythrocytes in the placenta. However, the pathomechanism of placental infection has not been thoroughly investigated.

Physiological roles and metabolism of γ-aminobutyric acid (GABA) in parasitic protozoa.

γ-aminobutyric acid (GABA) is a nonstructural amino acid that serves diverse functions in unicellular and multicellular organisms. Besides its widely established role in mammals as an inhibitory neurotransmitter, the diverse biological roles and metabolism of GABA in protozoan parasites have begun to be unveiled. GABA acts as either the intracellular signal or cell-to-cell messenger to mediate a variety of cellular responses that protect the parasites from environmental and host-derived stress.

Malaria diagnostic update: From conventional to advanced method.

Background: Update diagnostic methods play essential roles in dealing with the current global malaria situation and decreasing malaria incidence.

Aim: Global malaria control programs require the availability of adequate laboratory tests in the quick and convenient field.

Results: There are several methods to find out the existence of parasites within the blood.

The Relationship Between Fetal Weight with Sequestration of Infected Erythrocyte, Monocyte Infiltration, and Malaria Pigment Deposition in Placenta of Mother Giving Birth Suffering from Plasmodium Vivax Infection.

Background: Malaria in pregnancy can cause fatal complications by parasite sequestration mechanism, which can cause monocyte infiltration in the intervillous space. infection was significantly associated with malaria pigment in the placenta, indicating past subclinical infections.

Objective: This study aimed to determine the mechanism of in the pathogenesis of placental malaria and its relationship with LBW.

Effect of Metabolite Extract of subsp. on 3D7 in Vitro.

Background: Malaria eradication has been complicated by the repeated emergence of antimalarial drug resistances. We aimed to determine whether a metabolite extract of subsp. could decrease the viability of 3D7 in vitro.