Moderate versus ultra-hypofractionated locoregional breast radiotherapy: Results of a retrospective study during the covid-19 era.

Purpose: The use of ultra hypofractionated adjuvant breast radiotherapy for elderly patients was extended during the covid-19 pandemic. We compared its efficacy and safety versus moderate hypofractionation in elderly patients with breast cancer receiving locoregional radiotherapy at a single radiotherapy centre.

Methods: This retrospective analysis utilized routine patient data.

Exercise-induced hypoalgesia following blood flow restricted exercise.

Objectives: Assess the repeatability of exercise-induced hypoalgesia (EIH) following low-load resistance exercise with blood flow restriction (LL + BFR) and the magnitude of EIH following LL + BFR, high-load resistance exercise, and a control intervention 1-h after exercise.

Design: Crossover design.

Setting: University laboratory.

MAGNITUDE: Transcranial Magnetic Stimulation for Treatment-Resistant Obsessive-Compulsive Disorder: A Randomized Sham-Controlled Phase II Trial Protocol.

Unlabelled: Obsessive-Compulsive Disorder (OCD) is a chronic psychiatric condition with a lifetime prevalence of 2-3%. It significantly burdens quality of life and is associated with substantial economic and disease burdens. Cognitive-behavioral therapy and high-dose selective serotonin reuptake inhibitors are considered the first-line treatments for OCD.

Acute Effects of Running and Blood Flow Restriction on Gas Exchange and Perceptual Responses.

Lubiak, SM, Proppe, CE, Rivera, PM, Howard, MA, Prajapati, AJ, Shah, NM, Patel, NN, Hammer, SM, Trevino, MA, Dinyer-McNeely, TK, Richardson, LD, Roth, BL, Zak, RB, and Hill, EC. Acute effects of running and blood flow restriction on gas exchange and perceptual responses. J Strength Cond Res 39(3): e436-e443, 2025-The purpose of this investigation was to examine gas exchange and perceptual responses during discrete running bouts performed at different peak running speeds with and without blood flow restriction (BFR).

Internalization of help-seeking stigma and the moderating role of familism among Latine adults with chronic pain.

Latine adults with chronic pain face heightened stigmatization of seeking professional psychological help. However, research is needed to test whether stigma is internalized and to identify protective factors. We focus on familism, a value commonly found in collectivist cultures that emphasizes family bonds.

Muscle-specific neuromuscular responses during running with blood flow restriction.

The purpose of this investigation was to examine muscle excitation at maximal running capacity without blood flow restriction (BFR) relative to submaximal running bouts with BFR. Fourteen college-aged males randomly completed four, three-minute running bouts at 70, 80, and 90% of peak speed with BFR (70%, 80%, and 90%) and without BFR at 100% of their peak speed (100%). The surface electromyographic amplitudes of the vastus lateralis, rectus femoris, and vastus medialis muscles were assessed.

Epidemiological Study on Humans, Animals and Snails for Schistosomiasis in Two Endemic Municipalities Nearing Elimination in Bohol, the Philippines.

Purpose: A comprehensive survey was conducted to assess the prevalence of Schistosoma japonicum infection in humans, water buffaloes, and snails in the two endemic municipalities of Talibon and Trinidad in Bohol, Philippines, which are nearing elimination.

Methods And Results: Human stool and blood samples were collected from barangays with snail breeding sites, and results showed higher positivity rates using the rSjTPx-1-ELISA compared to the Kato-Katz technique. Human stool examination for showed a 0.

Therapeutic Efficacy of the Inositol D-Pinitol as a Multi-Faceted Disease Modifier in the 5×FAD Humanized Mouse Model of Alzheimer's Amyloidosis.

Background/objectives: Alzheimer's disease (AD), a leading cause of dementia, lacks effective long-term treatments. Current therapies offer temporary relief or fail to halt its progression and are often inaccessible due to cost. AD involves multiple pathological processes, including amyloid beta (Aβ) deposition, insulin resistance, tau protein hyperphosphorylation, and systemic inflammation accelerated by gut microbiota dysbiosis originating from a leaky gut.

Assessing the use of unstructured electronic health record data to identify exposure to firearm violence.

Objectives: Research on firearm violence is largely limited to people who experienced acute bodily trauma and death which is readily gathered from Inpatient and Emergency Department settings and mortality data. Exposures to firearm violence, such as witnessing firearm violence or losing a loved one to firearm violence, are not routinely collected in health care. As a result, the true public health burden of firearm violence is underestimated.

Healthy Drinks, Healthy Teeth - Ciunerkaq Tanqigtuq (The Future is Bright): A study protocol for a community-based, non-randomized sociobehavioral trial to reduce added sugar intake in Alaska Native Yup'ik children in the Yukon-Kuskokwim Delta.

Background: This study protocol describes a community-based intervention that will seek to reduce added sugar intake in Yup'ik Alaska Native children by targeting reductions in sugar-sweetened fruit drinks.

Methods: A two-group non-randomized design will be used to evaluate the intervention in three Yup'ik communities in Alaska focusing on children age 1 to less than age 12 years with a minimum enrollment target of 192 children. Families in the intervention arm will participate in a program consisting of five sessions plus four brief check-ins, all delivered by a Yup'ik Community Health Worker.

Seroprevalence of Schistosoma japonicum Infection Among Dogs and Water Buffaloes Using Recombinant Antigen ELISA in New Corella, Davao del Norte, Philippines.

Purpose: Animal reservoirs are important targets for controlling and eliminating schistosomiasis. Prevalence studies showed that dogs (Canis familiaris) and water buffaloes (Bubalus bubalis) are important reservoirs of S. japonicum.

Attention and processing speed tests: Normative data for Spanish-speaking adults in the United States.

Background: Hispanics/Latinos are the largest racial/ethnic group among underrepresented populations in the U.S. and multiple sociodemographic, cultural, and linguistic factors have been found to impact their performances on cognitive testing.

WHO-UCLA auditory verbal learning test: Normative data for Spanish-speaking adults in the United States.

Background: Hispanics are a significant demographic in the U.S., with diverse cultures and languages.

Executive function tests: Normative data for Spanish-speaking adults in the United States.

Background: Normative data for Spanish-speaking populations, particularly Hispanics in the U.S., is notably scarce.

The carbon isotope ratio of breath is elevated by short-term and long-term added sugar and animal protein intake in a controlled feeding study.

Background: The breath carbon isotope ratio (CIR) was recently identified as a noninvasive candidate biomarker of short-term added sugars (AS) intake.

Objectives: This study aimed to better understand the potential of the breath CIR as a dietary biomarker. We evaluated the effects of short-term and long-term intakes of AS, animal protein (AP), and related variables on breath CIR, in the context of typical dietary intake patterns.

Muscle Swelling and Neuromuscular Responses Following Blood Flow Restricted Exercise in Untrained Women.

There is conflicting evidence related to the prevalence and magnitude of exercise-induced muscle damage (EIMD) following four sets to volitional failure with BFR (BFR-F) or 75 total repetitions with BFR (1 × 30, 3 × 15, BFR-75). The purpose of this investigation was to examine muscle swelling, peak torque, and neuromuscular responses following BFR-75 and BFR-F. Thirteen untrained women completed unilateral isokinetic (120°s) leg extensions concentric-eccentric at 30% of their maximal voluntary isometric contraction (MVIC) using BFR-75 and BFR-F protocols, separated by 15 minutes.

Normative data for verbal fluency and naming tests in Spanish-speaking adults in the United States.

Background: Linguistic deficits are common across neurological and neurodegenerative disorders. Currently there are limited neuropsychological norms available for Spanish-speaking adults residing in the U.S.

A Moderate Blood Flow Restriction Pressure Does Not Affect Maximal Strength or Neuromuscular Responses.

Lubiak, SM, Lawson, JE, Gonzalez Rojas, DH, Proppe, CE, Rivera, PM, Hammer, SM, Trevino, MA, Dinyer-McNeely, TK, Montgomery, TR, Olmos, AA, Sears, KN, Bergstrom, HC, Succi, PJ, Keller, JL, and Hill, EC. A moderate blood flow restriction pressure does not affect maximal strength or neuromuscular responses. J Strength Cond Res 38(12): e727-e734, 2024-The purpose of this study was to examine the acute effects of blood flow restriction (BFR) applied at 60% of total arterial occlusion pressure (AOP) on maximal strength.

Progression and perceptual responses to blood flow restriction resistance training among people with multiple sclerosis.

Purpose: Resistance exercise can attenuate muscular impairments associated with multiple sclerosis (MS), and blood flow restriction (BFR) may provide a viable alternative to prescribing heavy training loads. The purpose of this investigation was to examine the progression of upper and lower body low-load (30% of one-repetition maximum [1RM]) resistance training (RT) with BFR applied intermittently during the exercise intervals (RT + BFR) versus volume-matched heavy-load (65% of 1RM) RT.

Methods: Men and women with MS (n = 16) were randomly assigned to low-load RT + BFR (applied intermittently) or heavy-load RT and completed 12 weeks (2 × /week) of RT that consisted of bilateral chest press, seated row, shoulder press, leg press, leg extension, and leg curl exercises.