Calcifying odontogenic cyst: clinicopathological features and immunohistochemical profile of 10 cases.

Background: Calcifying odontogenic cyst (COC) is an uncommon odontogenic lesion with few studies describing its immunohistochemical profile and proliferative activity reported in the literature.

Methods: Clinical and histological features and immunohistochemical expression of cytokeratins, Mel-CAM (CD146), bcl-2, PCNA and ki-67, in 10 cases of COC were studied.

Results: All 10 cases affected the maxilla, eight intraosseous and two peripheral.