Characterization, pro-inflammatory response and cytotoxic profile of bioaerosols from urban and rural residential settings in Pune, India.

Microbiota associated with airborne particulate matter (PM) is an important indicator of indoor pollution as they can be pathogenic and cause serious health threats to the exposed occupants. Present study aimed to investigate the level of culturable microbes associated with PM and their toxicological characterization in urban and rural houses of Pune city. Highest concentration of bacterial aerosols observed to be associated with PM size fraction in urban site (2136 ± 285 CFU/m) whereas maximum fungal concentration has been measured in rural houses (1521 ± 302 CFU/m).

Toxicological screening of airborne particulate matter in atmosphere of Pune: Reactive oxygen species and cellular toxicity.

Present study screened the toxicological assessment of airborne particulate matter (PM), mechanistic investigation, relationship between the physicochemical characteristics and its associated toxic response. The average concentration of both PM and PM exceeded the Indian National Ambient Air Quality Standards. In present study, PM bound metals; Fe, Cu, Cr, Ni, Mn, Pb, Cd, Zn, Sr and Co have been taken into account with total metal concentration of 0.

Genotoxic effects of PM and PM bound metals: metal bioaccessibility, free radical generation, and role of iron.

The present study was undertaken to examine the possible genotoxicity of ambient particulate matter (PM and PM) in Pune city. In both size fractions of PM, Fe was found to be the dominant metal by concentration, contributing 22% and 30% to the total mass of metals in PM and PM, respectively. The speciation of soluble Fe in PM and PM was investigated.

Chemical fractionation and health risk assessment of particulate matter-bound metals in Pune, India.

The present study deals with the assessment of sequential extraction of particulate matter (PM)-bound metals and the potential health risks associated with them in a growing metropolitan city (Pune) of India. The average mass concentration of both PM and PM exceeded the National Ambient Air Quality Standards. Significant seasonal variation in mass concentration was found for both size fractions of PM with higher values in winter season and lower in monsoon.

Role of metals in free radical generation and genotoxicity induced by airborne particulate matter (PM) from Pune (India).

In the present study, metal-facilitated free radical generation in particulate matter (PM) and its association with deoxyribonucleic acid (DNA) damage were studied. The examined data showed that the concentration of fine PM in Pune exhibited seasonal variations. Inductively coupled plasma-atomic emission spectrometry (ICP-AES) was used to examine the metal composition, which showed the presence of metals such as Cu, Zn, Mn, Fe, Co, Cr, Pb, Cd, and Ni.