Background: Single-photon emission computed tomography (SPECT) devices equipped with cadmium-zinc-telluride (CZT) detectors achieve high contrast resolution because of their enhanced energy resolution. Recently, thallium bromide (TlBr) has gained attention as a detector material because of its high atomic number and density.
Purpose: This study evaluated the clinical applicability of a SPECT system equipped with TlBr detectors using Monte Carlo simulations, focusing on 99mTc and 177Lu imaging.