A homogeneous hybridization magnetic biosensor based on electric field assistance for ultrafast nucleic acid detection.

Electrochemical biosensing is a sensitive strategy widely used in the field of nucleic acid detection. However, electrochemical biosensors generally involve time-consuming and labor-intensive probe immobilization processes. In this study, an electrochemical DNA biosensor based on homogeneous hybridization in solution was designed for nucleic acid detection without probe immobilization, which is different from most biosensors.

Rapid, specific and sensitive detection of in seafood by accelerated strand exchange amplification.

infectious diseases caused by seafood contamination may be life-threatening to people with weak immunity. The detection of the pathogen in aquatic foods is critical for reducing the outbreak of human -associated diseases. In this study, a highly sensitive, specific, and time-saving real-time narrow thermal-cycling amplification detection method was developed based on accelerated strand exchange amplification (ASEA).

Electrical potential-assisted DNA-RNA hybridization for rapid microRNA extraction.

Analysis of microRNAs (miRNAs) is important in cancer diagnostics and therapy. Conventional methods used to extract miRNA for analysis are generally time-consuming. A novel approach for rapid and sensitive extraction of miRNAs is urgently need for clinical applications.