A meta-analysis examined the effects of statin therapy on people living with HIV (PLWH), finding improvements in lipid profiles but also significant side effects that necessitate careful monitoring.*
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The analysis included data from 12 randomized controlled trials (RCTs) involving 8,716 participants, showing notable reductions in total cholesterol, LDL, and triglyceride levels, while also noting a higher rate of treatment discontinuation compared to placebo.*
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Overall, the benefits of statin therapy for PLWH, such as improved cholesterol levels, were found to outweigh the risks of side effects like muscle or liver issues.*