Orlistat improves endothelial function in obese adolescents: a randomised trial.

Aim: To investigate the effect of orlistat on endothelial function in obese adolescents.

Methods: Single-blind 10-week controlled trial of 67 normolipidaemic obese adolescents randomised into three groups. Group 1 (diet alone), Group 2 (diet and orlistat), Group 3 (diet, orlistat and exercise).

[Waist circumference reference values for screening cardiovascular risk factors in Chinese children and adolescents aged 7 - 18 years].

Objective: To explore the optimal threshold values of waist circumference (WC) in detecting the risk on cardiovascular (CV) among the Chinese children and adolescents.

Methods: Association of WC and CV risk factors were studied among 65 898 children and adolescents aged 7 - 18 years whose data were pooled from nine studies carried out in China. Receive-operating characteristic analysis (ROC) and logistic regression were employed to derive optimal age- and sex-specific waist circumference references for predicting the CV risk factors.

[Waist circumference distribution of Chinese school-age children and adolescents].

Objective: To study the distribution of waist circumference (WC) in a representative group of Chinese children for establishing the Chinese WC cut-off points.

Methods: Cross-sectional data obtained from 15 mainland provinces and Hong Kong were collected. There were 178 865 children and adolescents, aged 7 - 18 years-old in total.

Waist circumference reference values for screening cardiovascular risk factors in Chinese children and adolescents.

Objectives: To explore the optimal threshold values of waist circumference (WC) for detecting cardiovascular (CV) risk factors among Chinese children and adolescents.

Methods: Association of WC with CV risk factors was studied among 65,898 children aged 7-18 years whose data were pooled from nine previous studies in China. CV risk factors in this study included hypertension (blood pressure above 95 percentile levels), dyslipidemia (with one or more of the following three indexes: TG > or = 1.

Waist circumference distribution of Chinese school-age children and adolescents.

Background: Waist circumference (WC), a proxy measure of central body fat, is a better predictor than overall body fat for cardiovascular risk factors in both adults and children. WC cutoffs have been established in many countries, but the national WC reference has not been developed in China.

Objective: To study the distribution of WC in a representative group of Chinese children for establishing Chinese WC cutoff points.