Persistence of Parvovirus B19 in liver from transplanted patients with acute liver failure.

In this study, we investigated the presence of B19V in liver tissues from patients with acute liver failure (ALF) and evaluated the viral activity in infected liver. Serum and liver samples from 30 patients who underwent liver transplantation for ALF were investigated for B19V infection by real-time PCR, serological tests and examination of B19V mRNA (transcript) expression in the liver. The serum and liver samples from seven patients were B19V DNA positive (10-10 copies/ml).