Publications by authors named "Rita Wadetwar"
The present work describes the investigation of secondary metabolites produced by rhizospheric soil isolate with respect to partial purification, bioactivity, structural elucidation, and docking study. MIC (Minimum Inhibitory Concentration) of the fraction was found to be 16 µg/mL, 32 µg/mL, and 8 µg/mL against , , and respectively. The fraction exhibited an IC of 90.
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- The vaginal route offers advantages like better absorption and bypassing the liver's first-pass metabolism, making it a good method for drug delivery.
- Various challenges exist, such as pH levels and mucus variations, which can affect the effectiveness of this delivery method.
- Recent advancements in polymeric nanocarriers show promise in enhancing drug efficacy and release for vaginal applications, allowing for the delivery of complex therapeutic agents.