Publications by authors named "Rita S Alqubelat"
Cage-like microstructures via sequential Ugi reactions in aqueous emulsions.
Beilstein J Org Chem
August 2024
Cage-like microstructures were obtained in two steps by sequential Ugi reactions. At the first stage, submicron colloidal particles based on carboxymethylcellulose and chitosan with a domain structure were obtained in an aqueous suspension. In the second stage, the Ugi reaction was carried out on the surface of the Pickering emulsions with toluene.
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- This study focuses on using cross-linked carboxymethyl cellulose and chitosan particles to stabilize Pickering emulsions, showing their effectiveness in oil/water mixtures.
- The particles were created through a specific assembly method and analyzed for their size and structure, revealing that they are suitable for forming stable emulsions even at low concentrations.
- The research also highlights the successful encapsulation and controlled release of the natural compound piperine from these emulsions, suggesting potential applications for drug delivery systems.
The Ugi four-component condensation in diluted liposomal suspensions was used to prepare pectin-based submicron capsules. A set of isocyanides and aldehydes was used to optimize the synthesis of capsule shells. Modified sugar beet pectin was selected as a natural polymer with pronounced surface activity to create a capsule shell.
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