Labor induction with a combined method (pharmacologic and mechanical): A randomized controlled trial.

Introduction: The aim of this study was to compare the effectiveness of a combined misoprostol-Foley catheter induction of labor protocol against the current guidelines of our department.

Material And Methods: A randomized trial was conducted comparing two cervical ripening study groups: combined misoprostol-cervical Foley and the current department practice (misoprostol alone or dinoprostone alone). Women were stratified randomly according to parity for the two intervention groups.

Risk Factors for Positive Margins in High-Grade Cervical Intraepithelial Neoplasia After Transformation Zone Excision.

Objective: The aim of the study was to evaluate risk factors for positive margins on surgical specimens of patients submitted to transformation zone excision (TZE).

Materials And Methods: We conducted a retrospective study evaluating women submitted to TZE in our center, between 2012 and 2020. Our study population included only women with the diagnosis of high-grade intraepithelial lesion (HSIL) in the pathologic examination of the TZE surgical specimen.

Erosive Vulvar Lichen Planus and Risk of Vulvar Neoplasia.

Objective: The aim of the study was to assess the risk of vulvar cancer and precursors in a cohort of women with vulvar lichen planus (LP) and the clinical and therapeutic features of these patients.

Materials And Methods: A retrospective cohort study, including all the women with the diagnosis of vulvar LP, followed in one institution during a period of 11 years, was performed. Demographic and clinical data, as well as treatment, follow-up, and histology results, were evaluated.

Effect of obesity on labor duration among nulliparous women with epidural analgesia.

The aim of this study was to describe the effect of obesity on the duration of labor, specifically latent and active phases of labor, and on mode of delivery, among nulliparous women with epidural analgesia. We conducted a retrospective cohort study, comparing a sample of nulliparous obese women (body mass index ≥30 kg/m,  = 121) with a random sample of normal weight nulliparous (18.5 kg/m ≤body mass index ≤25 kg/m,  = 161).