Buprenorphine Induction in Trauma Patients With Opioid Use Disorder - A Single Center Experience?

Introduction: Buprenorphine is a Food and Drug Administration-approved therapy for opioid use disorder, with proven efficacy in treatment retention and reduction in opioid use and mortality. Low-dose buprenorphine initiation or microinduction is a novel means of initiation that may allow for an easier transition in patients. Trauma patients have high rates of opioid use disorder and patient directed discharges (PDD).

Pulmonary Function Testing in Dentists Versus Controls: A Pilot Study Exploring the Potential Respiratory-Related Occupational Hazards of Dentistry.

Objective: Minimal research exists evaluating respiratory-related occupational hazards associated with dentistry in the United States. The purpose of this study was to evaluate the pulmonary function of dentists as compared with controls.

Methods: This is a case-control study evaluating pulmonary function in dentists versus controls.

Hemolytic Crisis following Naphthalene Mothball Ingestion in a 21-Month-Old Patient with Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency.

Introduction: Naphthalene is an aromatic hydrocarbon that may be found in mothballs and deodorizers. Exposure can occur by ingestion or dermal absorption. We present a case of acute hemolysis requiring blood transfusion in a 21-month-old male with a history of glucose-6-phosphate dehydrogenase (G6PD) deficiency after ingestion of a naphthalene-containing mothball.

Opioid Toxidrome Following Grapefruit Juice Consumption in the Setting of Methadone Maintenance.

Background: Methadone is a synthetic mu-opioid receptor agonist used in the treatment of chronic pain and opioid dependence. Methadone is metabolized by several cytochrome P450 isoenzymes; primarily CYP3A4, CYP2B6, and CYP2D6 before renal and fecal elimination. Exposure to substances like grapefruit juice, that inhibit these isoenzymes may result in increased blood levels of methadone, and thus may manifest clinically as unexpected opioid toxicity.

Gadolinium Aspiration Following Inadvertent Endotracheal Tube Cuff Injection in a Pediatric Patient.

Introduction: Gadolinium-based contrast agents (GBCA) are frequently used for MRI contrast studies. We report a case of pulmonary aspiration secondary to inadvertent GBCA injection.

Case Report: A 12-year-old female with a past medical history significant for mitochondrial disorder, bronchial asthma, autism, recurrent urinary tract infection, epilepsy, developmental delay, dysautonomia, and thrombocytopenia was scheduled for a contrast-enhanced MRI study using gadoterate meglumine for urinary incontinence.

Urine uranium concentrations and renal function in residents of the United States--2001 to 2010.

Context: Animal model studies have demonstrated that subchronic oral uranium exposure is associated with renal dysfunction. Little is known about the effects of environmental exposure to uranium in humans.

Objective: To determine whether environmental exposure to uranium is associated with alterations in renal function among residents of the United States.

Change in perceived risk associated with marijuana use in the United States from 2002 to 2012.

Context: The role of a dynamic legal, medical, and social setting in affecting the perceived risk associated with smoking marijuana has not been well studied. We sought to determine whether there has been a change in the perceived risk associated with marijuana use over time.

Methods: A cross-sectional study was conducted using the 2002-2012 National Survey on Drug Use and Health.

Effect of single-dose Ginkgo biloba and Panax ginseng on driving performance.

Context: Panax ginseng and Gingko biloba are commonly used herbal supplements in the United States that have been reported to increase alertness and cognitive function.

Objective: The objective of this study was to investigate the effects of these specific herbals on driving performance.

Materials And Methods: 30 volunteers were tested using the STISIM3® Driving Simulator (Systems Technology Inc.

K2--not the spice of life; synthetic cannabinoids and ST elevation myocardial infarction: a case report.

Introduction: The adverse effects of synthetic cannabinoids are not well-described nor have they been thoroughly studied.

Case Report: A 16-year-old male with a past medical history of asthma and attention deficit hyperactivity disorder (ADHD) presented to the emergency department (ED) complaining of 24 h of substernal pressure associated with dyspnea, nausea, and vomiting. He reported smoking tobacco cigarettes daily and occasional marijuana use but denied recent use of marijuana.