Glycemic load and endometrial cancer risk in a case-control study of Canadian women.

Introduction: The evidence for a role of dietary carbohydrate intake with endometrial cancer risk is conflicting. We therefore evaluated the association between glycemic load (GL) and endometrial cancer in a population-based-case control study using a comprehensive quantitative food frequency questionnaire for the estimation of GL.

Methods: Diet in the year before the reference date was assessed with the self-administered Canadian Diet History Questionnaire in 511 cases and 980 controls in Alberta, Canada between 2002 and 2006.

Case-control study of the metabolic syndrome and metabolic risk factors for endometrial cancer.

Background: Metabolic syndrome may predict endometrial cancer risk better than diabetes, hypertension, dyslipidemia, dysglycemia, or weight alone, but few studies have examined this issue.

Methods: We conducted a population-based case-control study in Alberta, Canada (2002-2006) that included 515 incident endometrial cancer cases and 962 frequency age-matched controls. Data were collected through in-person interviews, anthropometric measurements, and 8-hour fasting bloods drawn either pre- or postsurgery.

Risk of endometrial cancer in relation to individual nutrients from diet and supplements.

Objective: Intake of nutrients may influence the risk of endometrial cancer (EC). We aimed to estimate the association of intake of individual nutrients from food and from food plus supplements with EC occurrence.

Design: A population-based case-control study conducted in Canada (2002-2006).

Case-control study of dietary patterns and endometrial cancer risk.

Dietary patterns, rather than intakes of specific foods or nutrients, may influence risk of endometrial cancer (EC). This population-based case-control study in Canada (2002-2006) included incident EC cases (n = 506) from the Alberta Cancer Registry and controls frequency age-matched to cases (n = 981). Past-year dietary patterns were defined using factor analysis of food frequency questionnaire data.

Quantitative assessment of thrombus burden predicts the outcome of treatment for venous thrombosis: a systematic review.

Purpose: Clot-burden change in patients receiving anticoagulant therapy, by predicting subsequent recurrent venous thromboembolism, may provide a clinically relevant surrogate endpoint of prognostic importance. The validity of this objective measure is yet to be established.

Methods: A PubMed search was performed to retrieve articles published up to December 2003.

D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review.

Background: Despite extensive literature, the diagnostic role of d-dimer for deep venous thrombosis (DVT) or pulmonary embolism (PE) remains unclear, reflecting multiple d-dimer assays and concerns about differing sensitivities and variability.

Purpose: To systematically review trials that assessed sensitivity, specificity, likelihood ratios, and variability among d-dimer assays.

Data Sources: Studies in all languages were identified by searching PubMed from 1983 to January 2003 and EMBASE from 1988 to January 2003.