Treatment-free remission in chronic myeloid leukemia: the patient perspective and areas of unmet needs.

In CML, treatment-free remission (TFR) refers to having a stable deep molecular response without the need for ongoing tyrosine kinase inhibitor treatment. Whilst recommendations exist about the technical management of stopping and re-starting therapy, much is still unknown about the experiences of those considering and undertaking TFR. This study sought to obtain the patient perspective, identify areas of unmet needs and create recommendations for improvements.

Individual Differences in Approach and Avoidance Inclinations Moderate the Effect of Self-Control Depletion on Ad-Lib Drinking.

Background: This study sought to examine how exerting self-control to inhibit stereotype use affects alcohol consumption. In addition, we sought to expand previous findings via examination of how individual differences in motivations to approach or avoid alcohol consumption interact with self-control depletion to determine the regulation of ad-lib drinking behavior.

Methods: Sixty-one social drinkers (31 female) were recruited to participate in a socially relevant self-control depletion task in which they were randomly assigned to 1 of 2 creative writing conditions: (i) the self-control depletion condition with explicit instructions to refrain from using stereotypes, or (ii) the nondepletion condition in which no instructions were given regarding the use of stereotypes.

Women Inmate Substance Abusers' Reactivity to Visual Alcohol, Cigarette, Marijuana, and Crack-Cocaine Cues: Approach and Avoidance as Separate Dimensions of Reactivity.

Despite the growing recognition for multidimensional assessments of cue-elicited craving, few studies have attempted to measure multiple response domains associated with craving. The present study evaluated the Ambivalence Model of Craving (Breiner et al., 1999; Stritzke et al.

A meta-analysis of the effectiveness of placebo manipulations in alcohol-challenge studies.

Our meta-analysis examined the impact of specific alcohol placebo procedures on two manipulation checks (participant reports of number of alcohol drinks consumed and subjective intoxication) to determine which procedures produced the smallest effect sizes in comparisons between alcohol and placebo conditions. Databases for the years 1990-2007 yielded 44 studies that met inclusion criteria. These were subjected to detailed coding of procedures pertinent to placebo effectiveness.

Effect of alcohol on race-biased responding: the moderating role of internal and external motivations to respond without prejudice.

Objective: This experiment was a systematic examination of how drinking, available response time, and levels of internal and external motivations to respond without prejudice interact to affect responses in a behavioral assessment of the race bias of social drinkers.

Method: Ninety-one white undergraduate social drinkers (45 women) were randomly assigned within gender to alcohol (expect alcohol/receive alcohol), placebo (expect alcohol/receive placebo), or simple no-alcohol control (expect no alcohol/receive no alcohol) conditions. Participants then performed a sequential priming task, the Weapons Identification Task, designed to assess race-biased responding, under nonspeeded (2,000 ms) or speeded (500 ms) instructional sets.