Opinion paper: Exercise for healthy aging.

The physical demands of daily life in developed countries have decreased remarkably during the last two centuries. General leisure time has increased and the age at retirement has decreased. General health has improved and life expectancy has increased.

Climacteric symptoms in middle-aged women with chronic somatic diseases.

Objectives: Chronic diseases may aggravate or simulate climacteric symptoms. Although acknowledged in clinical practice, there is a lack of research systematically analysing the association between chronic diseases and climacteric symptoms.

Study Design And Main Outcome Measures: Our study was a cross-sectional population-based study, which included 3421 women, aged 41-54 years.

A population-based survey of quality of life in middle-aged Finnish women.

Objective: Factors that cause a decrease in quality of life (QoL) among middle-aged women are contradictory. Given that previous studies have been presumably performed in ethnically heterogeneous populations, we evaluated the impact of socioeconomic and lifestyle factors on QoL in Finnish women because the Finnish population is ethnically homogenous.

Methods: A total of 6,408 women (aged 41-54 y) who were called for municipal screening mammography received a postal survey concerning their health-related issues.

Central sympatholytic therapy has anti-inflammatory properties in hypertensive postmenopausal women.

Objective: Postmenopausal phase expresses many unfavourable physiological changes that lead to increased risk for cardiovascular disease. We compared the effect of two sympatholytic antihypertensive drug treatments, the centrally acting imidazoline receptor-1 agonist moxonidine and peripherally acting beta-blocking agent atenolol on sensitive inflammatory markers in overweight postmenopausal women with diastolic hypertension.

Methods: This was a multicentre, multinational double-blinded, prospective study comparing moxonidine (0.

The expression of cyclooxygenase-1 and -2 in proliferative endometrium and endometrial adenocarcinoma.

Background: The activity of cyclooxygenase-2 (COX-2) is increased in inflammation and in several cancer types. We investigated the expression of COX-2, cyclooxygenase-1 (COX-1), nitric oxide synthase-2 (NOS-2) and nitric oxide synthase-3 (NOS-3) in normal proliferative and secretory human endometrium, and in endometrial adenocarcinoma.

Methods: Human endometrium was collected at hysterectomy.