Pyruvate formate lyase regulates fermentation metabolism and virulence of .

, a zoonotic pathogen, is commonly found as a commensal bacterium in the respiratory tracts of pigs. Under specific conditions, it becomes invasive and enters the blood, causing severe systemic infections. For , effective acquisition of carbon sources in different host niches is necessary for its survival.

Targeting AI-2 quorum sensing: harnessing natural products against Streptococcus suis biofilm infection.

The biofilm acts as a protective layer for Streptococcus suis (S. suis), contributing to the development of drug resistance and chronic infections. Autoinducer 2 (AI-2) quorum sensing represents the primary regulatory pathway governing biofilm formation in S.

Molecular mechanism and application of emerging technologies in study of bacterial persisters.

Since the discovery of antibiotics, they have served as a potent weapon against bacterial infections; however, natural evolution has allowed bacteria to adapt and develop coping mechanisms, ultimately leading to the concerning escalation of multidrug resistance. Bacterial persisters are a subpopulation that can survive briefly under high concentrations of antibiotic treatment and resume growth after lethal stress. Importantly, bacterial persisters are thought to be a significant cause of ineffective antibiotic therapy and recurrent infections in clinical practice and are thought to contribute to the development of antibiotic resistance.

Antimicrobial Resistance and Biofilm Formation of in Central China, with Evidence of a Rare Heteroresistance Strain to Gentamicin.

is a significant contributor to respiratory disease in pigs, leading to substantial economic losses in the swine industry worldwide. We isolated 52 strains from 542 samples collected from pigs with atrophic rhinitis and bronchopneumonia in central China. Multi-locus sequence typing identified two prevalent sequence types: ST6 (69.

Design of Lubricant-Infused Surfaces Based on Mussel-Inspired Nanosilica Coatings: Solving Adhesion by Pre-Adhesion.

Slippery liquid-infused porous surfaces (SLIPSs) have attracted wide interest with regard to their excellent liquid repellency properties and broad applications in various fields associated with anti-adhesion. However, the preparation processes depending on the chemical properties of the substrate and the poor stability of the lubricant layer hinder the practical applications. In this work, a facile method to fabricate SLIPSs based on the mussel-inspired polydopamine (PDA)-mediated nanosilica structures is demonstrated.

A porphyrin-based optical sensor membrane prepared by electrostatic self-assembled technique for online detection of cadmium(II).

An optical sensor membrane was prepared by electrostatic self-assembled technique for online detection of cadmium ion (II) (Cd(II)). The optical indicator 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin p-toluenesulfonate (TMPyP) was adsorbed on a hydrolyzed polyacrylonitrile (PAN) membrane by electrostatic attraction and further immobilized through layer-by-layer deposition of poly(allylamine hydrochloride) (PAH) and poly(sodium 4-styrenesulfonate) (PSS) on the membrane surface. The electrostatic self-assembly of polyelectrolytes on the membrane is influenced by pH and salt concentration of polyelectrolytes.