Publications by authors named "Rishang Lu"
Article Synopsis
- Pancreatic cancer is a serious disease that doesn’t show symptoms until it's very advanced, making it tough to treat, and surgery is currently the best method we have.
- Researchers studied a protein called TAGLN2 to see if it could control other proteins that help pancreatic cancer cells grow and spread.
- The study found that high levels of TAGLN2 in pancreatic cancer are linked to worse outcomes, and when they silenced another protein, ARPC5, it stopped TAGLN2 from making the cancer cells grow and spread.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
J Exp Clin Cancer Res
March 2024
Background: Pancreatic cancer (PC) is a highly malignant gastrointestinal tumor, which is characterized by difficulties in early diagnosis, early metastasis, limited therapeutic response and a grim prognosis. Therefore, it is imperative to explore potential therapeutic targets for PC. Currently, although the involvement of the Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) in the human growth of some malignant tumors has been demonstrated, its association with PC remains uncertain.
View Article and Find Full Text PDFUnveiling the role of PYGB in pancreatic cancer: a novel diagnostic biomarker and gene therapy target.
J Cancer Res Clin Oncol
March 2024
Purpose: Pancreatic cancer (PC) is a highly malignant tumor that poses a severe threat to human health. Brain glycogen phosphorylase (PYGB) breaks down glycogen and provides an energy source for tumor cells. Although PYGB has been reported in several tumors, its role in PC remains unclear.
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