Publications by authors named "Rishabh Hariharan"
Article Synopsis
- - The first audit of LGBTQ+ inclusivity in UK fertility care reveals significant shortcomings in clinical knowledge and cultural competence, particularly affecting transgender and gender diverse patients.
- - Despite some efforts to improve inclusivity, systemic barriers like cisheteronormativity and discrimination persist, leaving LGBTQ+ patients under-represented in both research and practice.
- - A checklist for enhancing LGBTQ+ inclusivity was co-developed with community members, focusing on cultural competence, clinical considerations, and online presence, highlighting the urgent need for better support and understanding in fertility care.
Research Question: What can three-dimensional cell contact networks tell us about the developmental potential of cleavage-stage human embryos?
Design: This pilot study was a retrospective analysis of two Embryoscope imaging datasets from two clinics. An artificial intelligence system was used to reconstruct the three-dimensional structure of embryos from 11-plane focal stacks. Networks of cell contacts were extracted from the resulting embryo three-dimensional models and each embryo's mean contacts per cell was computed.
With the growing understanding of in vitro fertilization and reproductive technology, the magnitude of studies related to embryonic evolution has also increased. The optimization of embryo selection is crucial to minimize the risk of multiple pregnancies and to guarantee successful implantation and pregnancy. On the second day of culture, the four-cell embryo can be shaped into different arrangements, such as tetrahedral and planar.
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