Publications by authors named "Risa Takao"
Article Synopsis
- A new compound called 6,9-dihydroxytetrangulol was extracted from a genetically modified strain of Streptomyces lividans TK23.
- The compound's chemical structure was determined through various spectroscopic methods.
- It demonstrated strong antibacterial properties against Staphylococcus aureus and moderate anticancer effects on HL-60 cancer cells.
Recent advances in genome sequencing have revealed a variety of secondary metabolite biosynthetic gene clusters in actinomycetes. Understanding the biosynthetic mechanism controlling secondary metabolite production is important for utilizing these gene clusters. In this study, we focused on the kinanthraquinone biosynthetic gene cluster, which has not been identified yet in Streptomyces sp.
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