Publications by authors named "Risa Morikawa"
Article Synopsis
- Sildenafil improves insulin sensitivity and enhances insulin secretion in β cells, particularly in the presence of other depolarizing stimuli.
- The drug operates independently of the traditional PDE5/cGMP pathway, primarily by increasing calcium influx through R-type voltage-dependent calcium channels.
- This study positions sildenafil as a potential antidiabetic medication and provides insights into a novel mechanism for insulin secretion.
Aims: The aim of this study is to investigate the effects of a low-carbohydrate staple food (i.e., low-carbohydrate bread) on glucose and lipid metabolism and pancreatic and enteroendocrine hormone secretion in comparison with meals containing normal-carbohydrate bread, without consideration of the carbohydrate content of the side dishes.
View Article and Find Full Text PDFThe kinetic and mechanistic profiles of three pharmaceutical spherical carbon adsorbents, Kremezin as the brand product and two generics (Merckmezin and spherical carbon adsorbent "Mylan"), were compared. Five non-ionic active pharmaceutical ingredients with molecular weights of 136.1-424.
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