Publications by authors named "Risa Kohno"
Article Synopsis
- Benzo[]pyrene (BaP) is a harmful air pollutant that causes inflammation in lung cells, specifically in the alveolar epithelium, by increasing NLRP1 expression while slightly reducing NLRP3 levels.
- BaP's effects on NLRP1 expression were linked to the aryl hydrocarbon receptor (AhR) and reactive oxygen species (ROS), suggesting that these pathways are involved in the inflammatory response.
- The study concluded that BaP could likely activate the NLRP1 inflammasome, contributing to ongoing lung inflammation from air pollution.
Fine atmospheric particles, such as PM, are strongly related to the onset and exacerbation of inflammatory responses leading to the development of respiratory and cardiovascular diseases. PM is a complex mixture of tiny particles with different properties (i.e.
View Article and Find Full Text PDFBackground: Tokyo, the capital of Japan, is a densely populated city of >13 million people, so the population is at high risk of epidemic severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. A serologic survey of anti-SARS-CoV-2 IgG would provide valuable data for assessing the city's SARS-CoV-2 infection status. Therefore, this cross-sectional study estimated the anti-SARS-CoV-2 IgG seroprevalence in Tokyo.
View Article and Find Full Text PDFAim: We explored the feasibility of a long-term but low-frequency psychological preventive intervention in a high school setting.
Background: High school students may experience depression; psychological interventions to improve social and cognitive skills may be useful to decrease such depression. A long-term but low-frequency intervention may be feasible in this setting because of its minimal time demands and lack of need for specialist human resources DESIGN: We conducted a single-arm longitudinal descriptive study with an intervention applied six times over 2 years in one high school.