Characteristics of Primary and Metachronous Gastric Cancers Discovered after Eradication: A Multicenter Propensity Score-Matched Study.

Background/aims: Gastric cancers develop even after successful eradication. We aimed to clarify the characteristics of early gastric cancers discovered after eradication.

Methods: A total of 1,053 patients with early gastric cancer treated by endoscopic submucosal dissection were included.

Duodenal Neoplasms of Gastric Phenotype: An Immunohistochemical and Genetic Study With a Practical Approach to the Classification.

Duodenal neoplasm of gastric phenotype (DNGP) is very rare, and details of its histopathologic, genetic, and biological features are still unclear. Frequent gene mutations in GNAS, KRAS, and APC have been reported in pyloric gland adenomas and fundic gland-type neoplasms (initially reported as low-grade adenocarcinomas) of the stomach. Here we retrospectively analyzed 16 cases of extra-ampullary DNGP (benign to malignant), and we examined the mucin immunoprofile and oncogene mutations (GNAS, KRAS, APC, BRAF, and CTNNB1).