The marine pufferfish Takifugu exascurus is considered unsafe for human consumption due to insufficient data on its toxicity.
Ten specimens collected from Japan were tested for toxicity and tetrodotoxin (TTX) levels using two methods: mouse bioassay and HPLC-FLD.
The study found that while the skin, liver, and ovaries of the fish were toxic, the testes and muscle were mostly non-toxic, although low levels of TTX were detected in the muscle of two specimens.