Interaction of a Phospholipid and a Coagulating Protein: Potential Candidate for Bioelectronic Applications.

In the present communication, we have investigated the interaction between a biomembrane component 1,2-dioleoyl--glycero-3-phosphocholine (DOPC) and a coagulating protein protamine sulfate (PS) using the Langmuir-Blodgett (LB) technique. The π- isotherm, π- characteristics, and analysis of isotherm curves suggested that PS strongly interacted with DOPC, affecting the fluidity of the DOPC layer. Electrical characterization indicates that PS as well as the PS-DOPC film showed resistive switching behavior suitable for Write Once Read Many (WORM) memory application.