Publications by authors named "Ringrose S"

Article Synopsis
  • - Mitochondrial dysfunction is a key early feature in major neurodegenerative diseases like Alzheimer's and Parkinson's, characterized by issues such as increased cell death and energy mismanagement.
  • - Inorganic polyphosphate (polyP) is a conserved molecule that regulates mitochondrial function and may serve as an alternative energy source to ATP, potentially impacting calcium and protein balance within mitochondria.
  • - The review highlights polyP as a promising pharmacological target to combat mitochondrial dysfunction in neurodegenerative disorders, while emphasizing the need for further research to clarify its role and effects.
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The paper analyses the impact of a priori determinants of biosecurity behaviour of farmers in Great Britain. We use a dataset collected through a stratified telephone survey of 900 cattle and sheep farmers in Great Britain (400 in England and a further 250 in Wales and Scotland respectively) which took place between 25 March 2010 and 18 June 2010. The survey was stratified by farm type, farm size and region.

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The welfare consequences of long-distance transportation of animals remain a controversial topic. Animals that stand for most of the long journey (especially if additional muscular activity is required to deal with postural instability) are at risk of developing fatigue. Previous observational studies of behaviour and physiology suggested either that sheep do not become markedly fatigued by long journeys or that previous methods did not adequately identify fatigue.

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The contribution of savannas to global carbon storage is poorly understood, in part due to lack of knowledge of the amount of belowground biomass. In these ecosystems, the coexistence of woody and herbaceous life forms is often explained on the basis of belowground interactions among roots. However, the distribution of root biomass in savannas has seldom been investigated, and the dependence of root biomass on rainfall regime remains unclear, particularly for woody plants.

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Savannas are globally important ecosystems of great significance to human economies. In these biomes, which are characterized by the co-dominance of trees and grasses, woody cover is a chief determinant of ecosystem properties. The availability of resources (water, nutrients) and disturbance regimes (fire, herbivory) are thought to be important in regulating woody cover, but perceptions differ on which of these are the primary drivers of savanna structure.

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For purposes of suggesting adaptive and policy options regarding the sustained use of forestry resources in Botswana, an analysis of the whole countrywide satellite data (showing the mean present distribution of vegetation in terms of species abundance and over all density) and the projection of vegetation cover changes using a simulation approach under different climatic scenarios were undertaken. The analysis revealed that changes in vegetation cover types due to human and natural causes have taken place since the first vegetation map was produced in 1971. In the southwest, the changes appear to be more towards an increasing prevalence of thorn trees; in the eastern part of the country where widespread bush encroachment is taking place, the higher population density suggests more human induced (agrarian-degradation) effects, while in the sparsely settled central Kalahari region, changes from tree savanna to shrubs may be indicative of the possible influence of climate with the associated effects of fires and local adaptations.

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Foci points, which are currently intensified by increased anthropogenic activities, have resulted in vegetation changes in the cattle-dominated grazing areas of Botswana. Bush encroachment species--for instance Acacia tortilis, A. erubescens, A.

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/ Management problems arise in semiarid rangeland that are characterized by marked wet and dry seasons because of forage deficiencies in the dry season. These natural vegetation rangelands can sustain livestock all year long when forage and senesced grass are available into the dry season. Seasonal range condition data are required to provide a basis for pasture management to help locate dry season cover and thereby minimize overstocking and degradation.

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Increased interest in environmental change issues has led researchers to consider more integrated approaches to change dynamics. This paper examines change in terms of land degradation in north-central Botswana from both biophysical and human perspectives. Although seasonal and periodic droughts were prevalent, analysis of rainfall data over the past 70 years revealed no downward trend.

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